The Powerpuff Girls: The Movie: Generations

The Powerpuff Girls: The Movie: Generations is a 2024 American animated superhero musical film produced by the Warner Animation Group. The film is directed by series developers Nick Jennings and Bob Boyle, from a screenplay by Alicia Chan, Grace Kraft, and Jaydeep Hasrajani and a story by Jake Goldman and Haley Mancini. It is based on The Powerpuff Girls created by Craig McCracken, the one-reel film Whoopass Stew by Craig McCracken, the 2014 special Dance Pantsed by David P. Smith, the anime Powerpuff Girls Z by Megumu Ishiguro, and the 2016 reboot developed by Nick Jennings and Bob Boyle. The film stars Amanda Leighton, Kristen Li, Natalie Palamides, Olivia Olson, Jennifer Hale, Kate Higgins, Tom Kenny, Roger L. Jackson, Olivia Colman, Catherine Cavadini, Tara Strong, and E.G. Daily. This film serves as the series finale of the 2016 reboot of The Powerpuff Girls, and the first installment of Warner Animation Group's Cartoon Network Cinematic Universe.

The Powerpuff Girls: The Movie: Generations was theatrically released on November 22, 2024 by Warner Bros. Pictures, in 2D, 3D, IMAX, IMAX 3D, RealD 3D, Dolby Cinema, and 4DX. The film received acclaim from critics, audiences, and fans of the original series, who praised the blend of live-action, traditional animation, and computer animation, style, voice acting, soundtrack, and musical numbers. It also crossed the billion dollar mark, grossing $2.798 billion against a budget of $90 million and became the highest-grossing film of 2024 and the highest-grossing film of all time. The Powerpuff Girls: The Movie: Generations won Best Animated Feature Film at the 82nd Golden Globe Awards, the 30th Critics' Choice Awards and the 97th Academy Awards, among several other awards and nominations. A sequel is in development.

The film is dedicated to Chuck McCann, voice of the Amoeba Boys in the classic series and 2016 reboot episode Viral Spiral, who died on April 8, 2018.

Synopsis
Blossom, Bubbles, and Buttercup have been saving Townsville for many years. But when a portal that the Professor recently invented starts malfunctioning, the Girls discover their past selves: the 1998-2005 Powerpuff Girls! To save their dimensions from being destroyed, they must team up with the 1998-2005 Girls to go through other dimensions, while also meeting their other past selves, such as the 2014 Girls, the 2006-2007 PPGZ's, and the 1992 Girls.

Plot
The film begins with a stage with the red curtains above. Bubbles thanks the audience for coming as she tells us that this is the story of how the Powerpuff Girls met their past selves and teamed up with them. She then starts reading the opening quotes (from the 1998-2005 series) on her paper. As she reads them, the curtains open to reveal a skyline of Townsville.

Powerpuff Girls 2016 Blossom, 2016 Bubbles, 2016 Buttercup, and Blisstina Utonium discover what it feels like to stick together, while also meeting up with Jared, Barry, the Derbytantes, and other classmates. The next day, 2016 Professor Utonium invents a time portal and the 2016 Girls are amused. Afterwards, the four get ready to board the school bus, and it leaves for Midway Elementary.

The bus stops at Midway Elementary, and as the four Girls enter the school, and 2016 Blossom sees Jared. Bliss asks 2016 Blossom if she's gonna talk to him, and 2016 Blossom tells her that she hasn't decided yet. Later, Ms. Keane, their teacher, teaches history to her class, while the Girls takes some notes from the lesson. Later at recess, 2016 Bubbles performs a musical number to her sisters. At lunchtime, Bliss talks to her sisters about a multiverse that contains all the main, parallel, and alternate worlds based on their world, to which Blossom, Bubbles, and Buttercup learn about.

Meanwhile, in a lair that sits in Townsville Volcano Mountain, in the center of Townsville Park, 2016 Mojo Jojo works on a new plan to destroy the Powerpuff Girls and Townsville too, when he discovers that the Professor has invented a time portal. 2016 Mojo Jojo realizes that the new plan is to also destroy the multiverse, so he hacks the newly-invented time portal, making it malfunction.

Later, when the Girls got back from school, they discover that the portal had been malfunctioning. After trying to fix it, the portal inadvertently brings in the 1998 Girls. They tell them that nothing is what is seems in all the dimensions, and that Mojo Jojo is planning to destroy the Townsville of the multiverse. The next day, the six girls fly over to their school, only for Miss Keane to realize that there were six Powerpuff Girls in the school, leaving her confused. They then fly over to the Mayor’s office, only for the Mayor to get confused about their differences and get his assistant Ms. Bellum to get them out. Back at home, the Professor is concerned about their differences and looks, as well as why the portal was malfunctioning, and tells the seven girls that their universes are getting destroyed. So he tasks the six girls to get more of their old selves to put together a team.

In their room, they think of a plan to stop Mojo Jojo by joining forces with each other. They later sneak into the Derbytantes' lair, thus sending the 1998 Girls to sneak up on Maylyn, who later discovers that there are two Buttercups, two Blossoms, and two Bubbleses. They later talk about why the portal had been malfunctioning. Bubbles tells the Derbytantes the truth about what happened. Once the seven Girls got home, the portal brings in the 2014 Girls who offer to help them with their mission.

In the lab, Bliss reveals to the Girls a Powerpuff Time Machine, and shows them the Orb of Main, Parallel, and Alternate Universes. The ten girls fly to different universes with a time machine: first the 1992 universe, then the 1998-2005 universe, the 2014 universe, the 1995 universe, the Powerpuff Girls Z universe, the Powerpuff Girls Doujinshi universe, and finally the live-action Powerpuff universe. On the way, they recruit the 1992 Girls, the 1995 Girls, the PPGZ Girls, the PPGD Girls, and the live-action Powerpuff Girls. Afterwards, they travel between other Powerpuff dimensions to get back to the 2016 universe.

Meanwhile, Mojo Jojo, assembles his team, which includes Fuzzy Lumpkins, Princess Morbucks, the Rowdyruff Boys, the Amoeba Boys, the Gangreen Gang, HIM, Duplikate, Bianca Bikini, Barbarus Bikini, the Sporde, Silico, Sedusa, Packrat, Manboy, and the other villains from other universes to form a team, so that they can defeat the Girls once they show up.

The Girls make it to the 2016 universe. They fly over to their house, and Professor Utonium agrees to have them stay with them for the training days. After a lot of days of training, the Girls fly off to Townsville. They face Mojo and his gang, and try to battle him, but they are all outnumbered. 2016 Blossom tries to unleash the other versions of the Powerpuff Girls using the Orb of Main, Parallel, and Alternate Universes, but when Bliss tries to stop her from doing so, 2016 Blossom pushes Bliss away. Bliss tries to use her telekinesis, but it doesn’t work. The villains easily defeat the Girls, and Mojo swats the Girls, and they land into the junkyard with a thud. After an argument between Bliss and 2016 Blossom, the Girls all split up.

2016 Bubbles gets heartbroken about what 2016 Blossom did to them and starts crying. After 1998 Bubbles, 1998 Buttercup, the 1992 Girls, the 1995 Girls, the PPGD Girls, the live-action Powerpuff Girls, the PPGZ Girls, and the 2014 Girls went home to their respective dimensions, 2016 Buttercup tells 2016 Bubbles that there's no end of friendship and 2016 Bubbles feels better and hugs 2016 Buttercup, and then they went home so 2016 Buttercup can watch a Space Tow Truck episode and 2016 Bubbles can go to sleep. She tells 2016 Buttercup good night and that she’ll see her tomorrow. Then, she hears crying in the other room. 2016 Bubbles walks through the doorway to Bliss’ room to see Bliss crying on her bed. She comforts Bliss and reminds her that she will always be a Powerpuff Girl and after having a good talk, the two hug. Afterwards, 2016 Bubbles tells Bliss good night, goes back to her room, and drifts to sleep.

Meanwhile that night, a sad 2016 Blossom is sitting alone in the middle of the junkyard. She starts crying because of the argument she and Bliss had earlier. 1998 Blossom comes to her and comforts her. 1998 Blossom talks with 2016 Blossom, and 1998 Blossom tells her that it is never too late to do the right thing. Unfortunately, 2016 Princess Morbucks and her 1998 counterpart kidnap the Blossoms and takes them back to the 1998-2005 universe, sending them to Mojo Jojo’s lair. The next day, 2016 Bubbles wakes up to a new day, and finds a letter on Octi’s head, so she reads it, and in shock, she discovers that the Blossoms have been kidnapped, so she tells 2016 Buttercup and Bliss about it, and then they tell 1998 Bubbles and 1998 Buttercup, who discovered that their Blossom has been kidnapped as well. The Bubbleses and Buttercups, as well as the other Powerpuff Girls arrive too. Bliss and the Girls fly to the 1998-2005 universe using the Powerpuff Time Machine.

Meanwhile, 2016 Mojo Jojo reveals to the Blossoms that he is now working for 1998 Mojo Jojo. The Mojo Jojos activate the killing machine to start erasing the Blossoms forever. The Girls arrive and were gonna rescue the two from the machine. However, they refused to rescue the two after 2016 Buttercup told them about how 2016 Blossom insulted Bliss yesterday. So they all left the two behind and went back to their respective dimensions

Later, they were all hanging out in Town Hall, but they were not happy. Bliss regrets denying the idea of unleashing Powerpuff Girls from other universes, and realizes that Blossom was right: the best way to defeat them is to unleash the Powerpuff Girls of Infinite Earths, and 2016 Buttercup realizes how much of a jerk she was about what she said. Bliss tells the Girls that she has to unleash the Powerpuff Girls of Infinite Earths because that’s what 2016 Blossom always wanted, and then tells 2016 Buttercup that they have to go back to the 1998-2005 universe to rescue the Blossoms, and 2016 Buttercup agrees. They gathered everyone from their universes again after they went home from refusing to rescue 1998 Blossom and 2016 Blossom, and using the Powerpuff Time Machine, they went back to the 1998-2005 universe, but this time, they actually rescue the two from the machine. The Buttercups unplug the machine. 2016 Blossom and Bliss reconcile, and the Girls promise to work together, this time as a team, and fly back to the 2016 universe.

2016 Blossom gives up her leadership to Bliss, who uses the Orb of Main, Parallel, and Alternate Universes to form the “Powerpuff Girls of Infinite Earths”: the Powerpunk Girls, the Powerpup Girls, the Powerpuff Animals, the 1920s Cartoon Girls, the dancing robotic Powerpuff Girls, Bunny, Bell, Bloom, Bullet, and many other versions of the Girls. They easily overpower the Villains, and then, Dynamo and Brambles take out the other bad guys. When Mojo Jojo and his crew have surrounded the Girls, Professor Utonium, the Derbytantes, and everybody else, come to their rescue, with the Derbytantes finally taking down the bad guys. Then, Mojo Jojo's evil primates arrive, but Bliss and 2016 Blossom work together to fight all the primates while singing Karmin’s “Brokenhearted”, joined by the 2016 Bubbles, 2016 Buttercup, the 1998 Girls, the 1995 Girls, the 1992 Girls, the 2014 Girls, the PPGZ girls, the PPGD Girls, the live-action Powerpuff Girls, Professor Utonium, The Mayor of Townsville, Ms. Bellum, Maylyn, and the Derbytantes. After the other villains are defeated, Mojo Jojo injects himself with Chemical X and grows into a giant monster, and starts destroying Townsville. The Professor reveals that he has brought an Antidote X with him, but 2016 Blossom sacrifices herself to defeat giant Mojo Jojo by plummeting him onto the ground, causing a huge explosion. The Antidote X shrinks Mojo down to his original size, battered and defeated.

All of the Girls, including Bliss, Professor Utonium, and Maylyn look for 2016 Blossom until Bliss finds 2016 Blossom’s unconscious body. Bliss tries to wake 2016 Blossom up, but it was no use. Devastated, Bliss hugs 2016 Blossom and starts crying as she mourns over her sister, who wakes up, and reveals to Bliss and the others that she has done what’s right. Bliss was happy that 2016 Blossom did the right thing, and 1998 Blossom says that she was proud of what 2016 Blossom has done. The police arrests all of the 2016 villains for all their crimes, while the other 1992, 1995, 1998, 2014, and PPGZ villains are returned back into their respective universes.

With the Townsvilles finally at peace, all of the Girls are sent home to their respective dimensions. One week later, Townsville has now become more peaceful than before. The portal is fixed, and the bad guys are taken to jail. The 2016 Powerpuff Girls are glad that they don’t have to endure another multiverse-threatening crossover for at least another year, and they make a promise to keep saving Townsville no matter what happens. The narrator says “And so once again, with the help of all of their past selves and main, parallel, and alternate versions, the day is saved, thanks to: The Powerpuff Girls! You know, it’s not hard to know this is the end of the series. I guess I’ll cut it off here. Good night everyone!” And then the song ends and the curtains close, ending the film and the series.

Main Characters

 * Amanda Leighton as:
 * 2016 Blossom
 * 2016 Berserk
 * Kristen Li as:
 * 2016 Bubbles
 * 2016 Brat
 * Natalie Palamides as:
 * 2016 Buttercup
 * 2016 Brute
 * Butterfingers
 * Barry Mackerbacker
 * Olivia Olson as:
 * Blisstina Francesa Francia Mariam Alicia “Bliss” Utonium
 * Blister
 * Toya Delazy voices Bliss in the African version, Wendy Ayche (Wengie) in the Australian version, Alesha Dixon in the UK version, Nancy Ajram in the Lebanon version, and Claudia Tagbo in the French version.


 * Tom Kenny as:
 * 2016 Professor Utonium
 * 2014 Professor Utonium
 * 1998 Professor Utonium
 * 2016 Talking Dog
 * 2014 Talking Dog
 * 1998 Talking Dog
 * 2016 Mayor of Townsville
 * 2014 Mayor of Townsville
 * 1998 Mayor of Townsville
 * The Narrator
 * 2016 Mitch Mitchelson
 * 2014 Mitch Mitchelson
 * 1998 Mitch Mitchelson
 * Jennifer Hale as:
 * 2016 Ms. Keane
 * 2014 Ms. Keane
 * 1998 Ms. Keane
 * 2016 Sedusa
 * 2014 Sedusa
 * 1998 Sedusa
 * 1998 Princess Morbucks
 * 2014 Princess Morbucks
 * Maribelle the Unicorn
 * Kate Higgins as Maylyn
 * Roger L. Jackson as:
 * 2016 Mojo Jojo
 * 2014 Mojo Jojo
 * 1998 Mojo Jojo
 * 1998 Butch
 * 2014 Butch
 * Olivia Colman as Powerpuff Time Machine Computer Voice
 * Catherine Cavadini as:
 * 1998 Blossom
 * 2014 Blossom
 * 1995 Blossom
 * 1998 Berserk
 * 2014 Berserk
 * Tara Strong as:
 * 1998 Bubbles
 * 2014 Bubbles
 * 1998 Brat
 * 2014 Brat
 * E.G. Daily as:
 * 1998 Buttercup
 * 2014 Buttercup
 * 1995 Buttercup
 * 1998 Brute
 * 2014 Brute
 * Kath Soucie as 1995 Bubbles
 * Jennifer Fried as the    Whoopass Girls (archival recordings)
 * Nicole Bouma as Blossom    Akatsutsumi
 * Maryke Hendrikse as    Bubbles Gōtokuji
 * Kelly Metzger as Buttercup    Matsubara
 * Meghan Trainor as PPGD Blossom
 * Anna Faris as PPGD Bubbles
 * Abby Elliott as PPGD Buttercup
 * Jake Goldman as Jared Shapiro
 * Danny Cooksey as 2016 Brick
 * Greg Cipes as 2016 Boomer
 * James Arnold Taylor as 2016 Butch
 * Adam McArthur as Blake
 * TBA as Bash
 * TBA as Breaker
 * Haley Mancini as 2016 Princess Morbucks
 * Eric Bauza as:
 * 2016 Slim
 * 2016 Bossman
 * 2016 Junior
 * 2014 Slim
 * 2014 Bossman
 * 2014 Junior
 * 1998 Slim
 * 1998 Bossman
 * 1998 Junior
 * 1995 Bossman
 * Tiny / 1995 Junior
 * Skinny Slim / 1995 Slim
 * Prince Charming
 * Jim Cummings as:
 * 2016 Fuzzy Lumpkins
 * 2014 Fuzzy Lumpkins
 * 1998 Fuzzy Lumpkins
 * 1995 Fuzzy Lumpkins
 * Jill Talley as Duplikate
 * Jason Kaye as Gnat
 * Lily Vonnegut as Bianca Bikini
 * Fred Tatasciore as:
 * 2016 HIM
 * 2014 HIM
 * 1998 HIM
 * Nick LaNobodyKnows
 * Earth Plow


 * Dee Bradley Baker as:
 * Barbarus Bikini
 * Chiru
 * Cheepy
 * Ben Diskin as the Sporde
 * Maurice LaMarche as:
 * Pug-Faced Paulie
 * Manboy
 * Jeff Bennett as:
 * Broccoloids
 * Janitaur
 * Commando Chipmunk
 * Jason Spisak as:
 * Silico
 * Packrat
 * Kevin Michael Richardson as:
 * 2016 Giant Fishballoon
 * 2014 Giant Fishballoon
 * 1998 Giant Fishballoon
 * Tom Kenny and Jeff Bennett as:
 * 2016 Ace
 * 2014 Ace
 * 1998 Ace
 * 2016 Snake
 * 2014 Snake
 * 1998 Snake
 * 2016 Lil’ Arturo
 * 2014 Lil’ Arturo
 * 1998 Lil' Arturo
 * 2016 Grubber
 * 2014 Grubber
 * 1998 Grubber
 * 2016 Big Billy
 * 2014 Big Billy
 * 1998 Big Billy
 * Daran Norris, Eric Bauza, John DiMaggio, and Mae Whitman as miscellaneous Townsville citizens
 * Josh Fadem as Donny the Unicorn
 * Jennifer Martin as:
 * 2016 Miss Bellum
 * 2014 Miss Bellum
 * 1998 Miss Bellum
 * Yuri Lowenthal as Townsville Citizen #1
 * Seth Green as Townsville Citizen #2
 * Dwight Schultz as Lester Van Luster
 * Greg Proops as Isosceles
 * John O’Hurley as Popsicles
 * Jeff Bennett as Tyrannosaurus Tex
 * Anais Fairweather as Jemoire
 * Kyle A. Carrozza as Harmadillo
 * Cindy Robinson as Erika the Red
 * James Kirkland as Bro Sharks
 * Laura Bailey as Bluebelle
 * Sonal Shah as Supna Nehru
 * Cree Summer as Edith / Green Wing
 * Travis Willingham as Absman


 * Julie Nathanson as:
 * 2016 Robin Snyder
 * 2014 Robin Snyder
 * 1998 Robin Snyder


 * Daran Norris as Stanley Practice
 * Susanne Blakeslee as Sandra Practice
 * Justin Roiland as Midway Elementary student #1
 * Daron Nefcy as Midway Elementary student #2
 * Phil LaMarr as Townsville Citizen #3
 * Rob Paulsen as:
 * 1998 Brick
 * 2014 Brick
 * 1998 Boomer
 * 2014 Boomer
 * Rubber Bandit
 * Townsville Citizen #4
 * Alex Hirsch as Townsville Citizen #5
 * Grey Griffin as Townsville Citizen #6
 * Roger Craig Smith as:
 * Schedulebot
 * Townsville Citizen #7
 * Bob LaGrange
 * Doug Nicholas as Townsville Citizen #8
 * Kate Micucci as Hope
 * Louis Chirillo as PPGZ Professor Drake Utonium
 * Cathy Weseluck as Ken Kitazawa
 * Simon Hill as Peach
 * Alec Willows as Mayor Mayer
 * Nicole Oliver as PPGZ Sara Bellum
 * Tabitha St. Germain as PPGZ Miss Keane
 * Michael Dobson as PPGZ Mojo Jojo
 * Mark Oliver as PPGZ HIM
 * Scott McNeil as PPGZ Fuzzy Lumpkins
 * Kelly Sheridan as Himeko Shirogane
 * Andrew Francis, Tabitha St. Germain, Maryke Hendrikse, Peter New, and Richard Ian Cox as:
 * PPGZ Ace
 * PPGZ Snake
 * PPGZ Lil Arturo
 * PPGZ Grubber
 * PPGZ Big Billy
 * Richard Ian Cox, Brian Drummond, Tabitha St. Germain as:
 * Silk Hat
 * Poncho
 * Violet
 * Rebecca Shoichet as PPGZ Sedusa
 * Alberto Ghisi, Aidan Drummond, and Kathleen Barr as:
 * RRBZ Brick
 * RRBZ Boomer
 * RRBZ Butch
 * Chantal Strand as Miko Shirogane
 * Robyn Lively as Live-Action Sarah Bellum
 * Donald Faison as Live-Action Professor Drake Utonium
 * Nick Podany as Joseph “Jojo” Mondel Jr.
 * Marcia Adams and Sage Shirley as Pedestrians
 * Carl Anthony Nespoil as Cop
 * Andy Samberg as C
 * Jorma Taccone as N

Powerpuff Girls of Infinite Earths voices

 * Tara Reid, Brittany Murphy and Paris Hilton as:
 * 1998 (MAD Tv S9) Powerslut Girls
 * 2014 (MAD Tv S9) Powerslut Girls
 * 2016 (MAD Tv S9) Powerslut Girls
 * TBA as 2 Broke Blossom (MAD)
 * TBA as 2 Broke Bubbles (MAD)
 * TBA as 2 Broke Buttercup (MAD)
 * TBA as Blush
 * TBA as Blue
 * TBA as Buzzly


 * Lara Jill Miller as Bunny
 * Christine Cavanaugh (via archival recordings) as 1998 Bunny
 * Kristen Bell as Bell
 * Rachel Bloom as Bloom
 * Kate Micucci as Bullet
 * Eden Sher voices the squirrel version of Bullet
 * Alessia Cara as Bailey
 * Tina Fey as Banana
 * Charlyne Yi as Brownie
 * Kimaya Thais as Butterfly
 * Sophie Reynolds as Bouquet
 * Abbi Jacobson as Violet
 * TBA as Marcus
 * TBA as Shirley A.K.A. "Yesenia"
 * TBA as JRuff
 * TBA as 1998 Adult Blossom
 * TBA as 1998 Adult Bubbles
 * TBA as 1998 Adult Buttercup
 * TBA as Blair
 * TBA as Buddy
 * TBA as Bynum
 * TBA as Inferno
 * Demi Lovato as 2016 Teenage Blossom
 * Kimiko Glenn as 2016 Teenage Bubbles
 * Sabrina Carpenter as 2016 Teenage Buttercup
 * Sugar Lyn Beard as:
 * 1920s Cartoon Powerpuff Girls
 * 1930s dark and monochromatic Powerpuff Girls
 * Powerpuff Cookies
 * TBA as Powbypuff Girls (Brush, Bobo and Butterfly)
 * Amanda Leighton as:
 * Walrus Blossom
 * Elderly Blossom
 * Time Dasher Blossoms
 * Teen Titans Go! Blossom
 * LEGO Blossom
 * Funko Blossom
 * Blossom 2
 * Blossom 3
 * Astronaut Blossom
 * Zombie Bread Blossom
 * Rapper Blossom
 * Trouble Clef Blossom
 * Number Zero Blossom
 * Witch Blossom
 * Mermaid Blossom
 * Rockly Blossom
 * Kristen Li as:
 * Bee Bubbles
 * Elderly Bubbles
 * Teen Titans Go! Bubbles
 * Phantom Bubbles
 * LEGO Bubbles
 * Funko Bubbles
 * Rapper Bubbles
 * Trouble Clef Bubbles
 * Number Five Bubbles
 * Witch Bubbles
 * Bubbs Wonder
 * Mermaid Bubbles
 * Rockly Bubbles
 * Natalie Palamides as:
 * Flamingo Buttercup
 * Elderly Buttercup
 * Teen Titans Go! Buttercup
 * LEGO Buttercup
 * Funko Buttercup
 * Blundered Buttercup
 * Musclecup
 * Droid Buttercup
 * Math Queen Buttercup
 * Rapper Buttercup
 * Trouble Clef Buttercup
 * Witch Buttercup
 * Green Batman
 * Mermaid Buttercup
 * Rockly Buttercup
 * Olivia Olson as:
 * Dolphin Bliss
 * Elderly Bliss
 * Teen Titans Go! Bliss
 * LEGO Bliss
 * Funko Bliss
 * Lolita Bliss
 * Psycho Bliss
 * Wonder Woman Bliss
 * Muscular Bliss
 * Ninja Bliss
 * Papaya Bliss
 * Spider-Bliss
 * Witch Bliss
 * Mermaid Bliss
 * Bliss Cookie
 * Catherine Cavadini, Tara Strong, and E.G. Daily as:
 * Steamypuff Girls
 * Prehistoric Puff Girls
 * Liberty Belle, Harmony Bunny, and Mange
 * Powerplump Girls (Blimp, Bloated and Butterball)
 * Micropuff Girls (Micro Blossom, Micro Bubbles and Micro Buttercup)
 * Eden Sher as:
 * Powerpup Girls (Puppy Blossom, Puppy Bubbles, Puppy Buttercup, and Puppy Bliss)
 * Chickenpuff Girls (Chicken Blossom, Chicken Bubbles, Chicken Buttercup, and Chicken Bliss)
 * Charli XCX as Bee
 * Dana Davis as Suzie
 * Abby Elliott as Belladonna
 * Kylie Cantrall as Bling
 * Brenda Song as Barasia
 * Anna Akana as Bulaklak
 * Marlow Barkley as Young Live-Action Blossom
 * Ella Allan as Young Live-Action Bubbles
 * Mia Allan as Young Live-Action Buttercup
 * Lauren Jauregui as Bleed
 * Normani Kordei as Beanie
 * Dinah Jane as Blitz
 * Camilla Cabello as Beachball
 * Ally Brooke as Banshee

Other Characters

 * TBA as Professor Publicity (MAD Tv S9)
 * TBA as 2 Broke Professor Utonium (MAD)
 * TBA as 2 Broke Fuzzy Lumpkins (MAD)
 * TBA as 2 Broke Mojo Jojo (MAD)
 * TBA as 2 Broke HIM (MAD)

Additional Voices

 * Frank Welker
 * Rob Paulsen
 * Josh Keaton
 * Trevor Devall
 * Crispin Freeman
 * Wally Wingert
 * Drake Bell
 * Candi Milo
 * Lacey Chabert
 * Kari Wahlgren
 * Lloyd Sherr
 * Jason Alexander
 * Janice Kawaye
 * Seth MacFarlane
 * Carolyn Lawrence
 * Carlos Alazraqui
 * Jessica DiCicco
 * Laraine Newman
 * Tom Kenny
 * Ben Schwartz
 * Debi Derryberry
 * Audrey Wasilewski
 * Nika Futterman
 * Tara Strong
 * Edgar Wright
 * Wes Anderson
 * Nolan North
 * Mark Hamill
 * Rachael MacFarlane
 * Adam DeVine
 * Flula Borg
 * S. Scott Bullock
 * Fred Tatasciore
 * Tress MacNeille
 * Andy Richter
 * Jess Harnell

In the UK, African, and Australian versions, Kate Garraway and Ben Shephard appear as themselves, and replace Bob LaGrange and Nick LaNobodyKnows in the news report scene.

The Cash Money Crew, the Mole Men, the construction worker monster, Mr. Fluff-n-Stuff, Infernus, Manbot, the Robo-Referee, the Bronze Boogie Boarder, the Cowgirl, Gerald, Jack, Jerry, Laura, Trent, the Bull, the Hamburguer Turtle, One Claw McCraw, the Bank Robbing Gang, Betty, Big Ben, Mascumax, Billy, Chief of Police, Down Unda Mate, E-Male, Enrique, Ernst, Farouk, Fredirico Chang, Joey Finkelmeyer, Lloyd & Floyd Floyjoydson, Mandingo, Maria Guadalupe O’Flannigan, Ming, Mr. Anoush, Mucho Muchacho, Mushu Gai Man, Nadia, Officer Perez, Pablo, Pesos Bill, Phil Anthropist, Philip, Philipe, Poehler Fields, Ratman, Salami Swami, Shaquille Silverstein, Sgt. Pepper, Sosumi Bline, Talia, Teddy, Trevor, Wes Goingon, Ya-Mon, Valentino, Chicken Monster, Claws Monster, Cyclops, Dragon Monster, the Elders, the Giant Ant, the Giant Blue Octopus, the Giant Crab, the Giant Fish Monster, the Giant Fish Monster, Jerome, the Little Monster, the Maggot Monster, the Methane Monster, the Oil Monster, the Red Claw Monster, the Swampy Monster, Steve, Deb Yutont, Kameyari Takimo, the Kindergarten Teacher, Mr. Looper, the Snow Queen, the Pug-Thugs, and the Derbytantes also appear in the film. Dynamo and Brambles also appear, but do not have any dialogue.

The younger versions of the live-action Powerpuff Girls are set to appear.

Mojo Jojo’s evil primates, including Rocko Socko, Ojo Tango, Hotta Watta, and Killa Drilla, appear as well, with Frank Welker, Kevin Michael Richardson, and Rob Paulsen reprising their roles from The Powerpuff Girls Movie (2002).

Development
After Warner Animation Group and Cartoon Network started development on films for a shared Cartoon Network universe, developers Nick Jennings and Bob Boyle announced a sequel to The Powerpuff Girls Movie for November 2024. This resulted in the 2016 reboot of The Powerpuff Girls being brought back by Cartoon Network Studios on August 14, 2023 and renewing it for two more seasons (Seasons 4 and 5), making this reboot conclude after five seasons (as well as the musical movie). All cringe and toilet humor in this reboot were permanently removed from the series (meaning no more twerking or outdated memes from Season 4 onward), as musical numbers, a lot of heart, and heartwarming messages were put in to replace the cringe and toilet humor previously used in Seasons 1-3.

In response to The Powerpuff Girls: The Movie: Generations, as well as Warner Animation Group collaborating with Cartoon Network Studios, Cartoon Network Studios Europe, Warner Bros. Animation, Williams Street, and Cartoon Network Latin America Original Productions to kickstart the Cartoon Network Cinematic Universe, the 2016 reboot of The Powerpuff Girls will be brought back by Cartoon Network Studios on August 14, 2023 and renew it for two more seasons (Seasons 4 and 5), making this reboot conclude after five seasons (as well as the musical movie). All cringe and toilet humor previously used in Seasons 1-3 of this reboot will be permanently removed from the series (meaning no more twerking or outdated memes from Season 4 onward), and just like Rise of the Teenage Mutant Ninja Turtles, the 2017 reboot of DuckTales, and Season 5 of the 2016 Ben 10 reboot, it will have an action-packed tone, dark elements, clever writing, and creativity of the original, four things that the first three seasons lacked. It will also have the charm of the original, as it will have more crime-fighting and less slice-of-life scenes. It will no longer try to be hip; instead it will be more serious, and Seasons 4 and 5 will feel like an actual reboot that’s done right.

The trio in Seasons 4 and 5 of the reboot will be added up to four, with Blisstina being the newest member of the group.

Blossom, Bubbles, and Buttercup will also improve on their singing during these seasons.

The fourth season will last the from August 4, 2023 to February 8, 2024, while the fifth season will last from February 9, 2024 to November 22, 2024.

Starting with these seasons, the characters from the original series will redeem themselves and revert to their original selves:


 * Blossom’s 2016 counterpart will revert from an over-reactive, nagging, and exaggerating OCD neurotic perfectionist into a leader and the smart girl of the group, and also the most rational, meaning it's her plans that contribute to victory, much like her 1998 counterpart. However, she knows not everything has to go her way.
 * Bubbles’s 2016 counterpart will revert from a childish, crybaby, whiny, and stereotypically girly "girl" into a cute girly girl of the group who is the most optimistic and shy, meaning it's her openness to friendship that sometimes allows the girls to gain an upper hand by not fighting without a reason, much like her 1998 counterpart. In addition, she will also have her own Ice Form (based on the Ice Form/Suit Power-up from the Super Mario franchise), and a kind heart.
 * Buttercup’s 2016 counterpart will revert from a tomboyish clichéd bully into a sporty, no-nonsense tomboy who is always eager for a good fight, making her the key for overpowering enemies that can only be taken head on, much like her 1998 counterpart.
 * Blisstina Utonium’s characterization will be heavily improved, going from a teenage girl stereotype into a kind and supportive teenage sister to the group who always participates in fighting crime with her sisters.
 * Professor Utonium's 2016 counterpart will revert back to his characterization that he had in the classic 1998 series after he was flanderized into an unfunny idiotic dad trope in the first three seasons of the 2016 reboot.
 * Mojo Jojo’s 2016 counterpart will revert back to his characterization that he had in the classic 1998 series and will utilize his famous language and speech patterns again, after he was flanderized into a stereotypical villainous elitist who used to speak in the third person in the first three seasons of the 2016 reboot.
 * The Mayor of Townsville's 2016 counterpart will revert back to his characterization that he had in the classic 1998 series after he was flanderized into an unfunny comic relief in the first three seasons of the 2016 reboot.
 * Princess Morbucks’ 2016 counterpart will revert back to her characterization that she had in the classic 1998 series, after she was flanderized into a stereotypical famous girl in the first three seasons of the 2016 reboot.

Various characters from the 2016 reboot, such as Jared Shapiro, Manboy, Bianca Bikini, Packrat, Gnat, Silico, Donny, Pug-Faced Paulie, Duplikate, Erika the Red, and Supna Nehru, will also have their characterizations heavily improved.

Seasons 4 and 5 will be much darker than the original series, but not too dark to the point where it’s super edgy. As they say, the tone knows when to have its darker moments and when to have its lighter moments. Nothing here is too inconsistent tone-wise.

While the 2016 reboot will be more serious in Seasons 4 and 5, it will also have a few funny moments here and there within them to not make these seasons too serious, and these jokes will be done better than the previous three seasons.

One of the other additions to this reboot is that Blisstina will have her own bedroom, with a front doorway that leads straight to the Girls’ bedroom. The soundtrack album for the entire reboot will be available on WaterTower Music. Seasons 4 and 5 will also mark the return of Sedusa and Ms. Bellum, with Jennifer Hale and Jennifer Martin reprising their roles respectively. The Powerpuff Hotline, first seen in the episode “Puffdora’s Box”, will also return in Seasons 4 and 5, and will be in tandem with its smartphone counterpart. The narrator and the iconic ending hearts will also be used in every episode of Seasons 4 and 5. The narrator also will open every episode of Seasons 4 and 5 with the phrase: “The City of Townsville…” As a result of being renewed for two more seasons, the 2016 reboot of The Powerpuff Girls will be airing on the Cartoon Network channel again.

The first episode of Season 4 will focus on Blossom, Bubbles, Buttercup, and Professor Utonium giving Bliss a new room, after she quit the UPB to spend time with her family, while the second episode focuses on Blossom, Bubbles, Buttercup, and Bliss attending space camp for two weeks, and Blossom, Bubbles, and Buttercup explain to Bliss the events of Home, Sweet Homesick, while the four try the park attractions and carnival rides, and the third episode features Ms. Bellum returning to Townsville after she cut her vacation days short due to missing him.

Danny Cooksey, Greg Cipes, and James Arnold Taylor will voice Brick, Boomer, and Butch respectively in Seasons 4 and 5 and The Powerpuff Girls: The Movie: Generations. Adam McArthur, who is known for voicing Marco Diaz from Star vs. the Forces of Evil, will voice Blake, the fourth Rowdyruff Boy. These seasons will be in tandem with the 1998 Powerpuff Girls revival by Hanna-Barbera Studios Europe.

Starting with Season 4, Blossom, Bubbles, and Buttercup will go back to wearing their nightgowns for sleepwear. In addition, Bliss also will also have her own nightgown for sleepwear in light purple. She will also have her own swimsuit.

Despite the character designs being the same, the themes of Seasons 4, 5, and 6 will be taken much more seriously thanks to better storytelling and more time to flesh them out properly.

As a result of Seasons 4 and 5, much like Season 5 of the 2016 reboot of Ben 10, the animation will be brilliant and a MASSIVE step-up from the previous three seasons, as there will also be no animation errors in these seasons. Seasons 4 and 5 will be much more faithful to the original source material than the last three seasons. Blossom will still have a crush on Jared, Bubbles will still be a computer geek, and Buttercup will still be good at math. Pokey Oaks Kindergarten will be fixed and reopen from Season 4 onward. Mitch Mitchelson will also return in the 2016 reboot, with Tom Kenny reprising his role. There will also be several tear-jerking and heartwarming moments. Despite the character designs being the same, the themes of Seasons 4 and 5 will be taken much more seriously thanks to better storytelling and more time to flesh them out properly. There will also be no continuity errors. The script-writing and writing will also become massive improvements. In addition, Julia Vickerman will not be involved with Seasons 4 and 5. Nick Jennings and Bob Boyle will be the official executive producers of the reboot, starting with Season 4, as Craig McCracken will be busy on his own Powerpuff Girls and Foster’s Home for Imaginary Friends revivals.

Animation
The 2D animation has been handled by South Korean animation studios Sunmin Image Pictures (2016 Powerpuff Girls) and Rough Draft Studios South Korea (1998 Powerpuff Girls) for Cartoon Network Studios in Burbank, California, while CGI animation for the 2014 Powerpuff Girls was handled at British CGI animation studio Passion Pictures, and the anime-style animation for the Powerpuff Girls Z characters got handled at Japanese animation studio Toei Animation, while the animation for the Funko Powerpuff Girls will be provided by Funko Animation Studios. The animation for the Teen Titans Go! versions of the Powerpuff Girls has been handled at Copernicus Studios and Bardel Entertainment, while the additional computer animation was handled by Sony Pictures Imageworks, Reel FX Creative Studios, and Industrial Light & Magic, and Illumination (animation by Illumination Studios Paris) as a result of Cartoon Network’s partnership with Universal and Illumination. Computer animation was also used for when all versions of the Powerpuff Girls were thrown to a junkyard wall, which that scene had them be thrown with ragdoll physics. As a result, CGI models had to be made for all of them. Additional live-action scenes have also been recorded at Warner Bros. Studios in Burbank, California, and Warner Bros. Studios, Leavesden.

Casting
On June 19, 2023, Amanda Leighton was cast as 2016 Blossom. This was followed by the casting announcements of Kristen Li, Natalie Palamides, Olivia Olson, Bill Hader, Zach Woods, Nick Kroll, Jennifer Hale, Kate Higgins, Tom Kenny, Roger L. Jackson, Cathy Cavadini, Tara Strong, and E.G. Daily the next day. On the same day, Tom Kenny confirmed that he will be voicing 2016 Professor Utonium, 1998 Professor Utonium, and the Talking Dog, replacing Tom Kane following his retirement from voice acting. Fred Tatasciore also replaces Kane as 2016 HIM and 1998 HIM.

Songs written by Hannah Watanabe-Rocco, Tristan Sedillo, and Mike Reagan
First musical number performed by: Amanda Leighton, Kristen Li, Natalie Palamides, and Olivia Olson Sung by: 2016 Blossom, 2016 Bubbles, 2016 Buttercup, and Blisstina Utonium Written by: Hannah Watanabe-Rocco, Tristan Sedillo, and Mike Reagan

Second musical number performed by: Kristen Li Sung by: 2016 Bubbles Written by: Hannah Watanabe-Rocco, Tristan Sedillo, and Mike Reagan

Third musical number performed by: Amanda Leighton, Kristen Li, Natalie Palamides, Olivia Olson, Cathy Cavadini, Tara Strong, and E.G. Daily Sung by: 2016 Blossom, 2016 Bubbles, 2016 Buttercup, Blisstina Utonium, 1998 Blossom, 1998 Bubbles, and 1998 Buttercup Written by: Hannah Watanabe-Rocco, Tristan Sedillo, and Mike Reagan

Fourth musical number performed by: Olivia Olson Sung by: Blisstina Utonium Written by: Hannah Watanabe-Rocco, Tristan Sedillo, and Mike Reagan

Fifth musical number performed by: Cathy Cavadini, Tara Strong, and E.G. Daily Sung by: 1998 Blossom, 1998 Bubbles, 1998 Buttercup, 2014 Blossom, 2014 Bubbles, and 2014 Buttercup Written by: Hannah Watanabe-Rocco, Tristan Sedillo, and Mike Reagan

Sixth musical number performed by: Nicole Bouma, Maryke Hendriske, and Kelly Metzger Sung by: Blossom Akatsutsumi, Bubbles Gōtokuji, and Buttercup Matsubara Written by: Hannah Watanabe-Rocco, Tristan Sedillo, and Mike Reagan

Seventh musical number performed by: Kristen Li and Natalie Palamides Sung by: 2016 Bubbles and 2016 Buttercup Written by: Hannah Watanabe-Rocco, Tristan Sedillo, and Mike Reagan

Eighth musical number performed by: Amanda Leighton and Cathy Cavadini Sung by: 1998 Blossom and 2016 Blossom Written by: Hannah Watanabe-Rocco, Tristan Sedillo, and Mike Reagan

Ninth musical number performed by: Olivia Olson Sung by: Blisstina Utonium Written by: Hannah Watanabe-Rocco, Tristan Sedillo, and Mike Reagan

Tenth and final musical number performed by: Amanda Leighton, Kristen Li, Natalie Palamides, Olivia Olson, Josh Fadem, Kate Higgins, Jennifer Hale, Tom Kenny, Jennifer Martin, Jake Goldman, The Powerpuff Girls Movie 2 Cast Sung by: Blossom, Bubbles, Buttercup, Blisstina Utonium, Donny, Maylyn, Ms. Keane, Professor Utonium, the Mayor of Townsville, Miss Bellum, Jared Shapiro, and the people of Townsville Written by: Hannah Watanabe-Rocco, Tristan Sedillo, and Mike Reagan

End Credits Songs

 * American Girl - Bonnie McKee
 * Me & My Girls - Fifth Harmony
 * Who’s Got The Power? - Tacocat
 * The Powerpuff Girls Movie 2: Generations End Credits Music - John Debney

Score tracks by John Debney

 * 1) The City of Townsville - John Debney
 * 2) The Portal - John Debney
 * 3) Amoeba Boys - John Debney
 * 4) 1998 Girls - John Debney
 * 5) Sneaking Into The Derbytantes' Lair - John Debney
 * 6) Maylyn / Bubbles' Recap - John Debney
 * 7) 2014 Girls - John Debney
 * 8) Blisstina - John Debney
 * 9) Time Travel - John Debney
 * 10) Mojo Jojo - John Debney
 * 11) Arrival To The 1992 Universe - John Debney
 * 12) This Is Our Room - John Debney
 * 13) Tokyo City / New Townsville - John Debney
 * 14) Return To 2016 Townsville - John Debney
 * 15) Trying To Defeat Mojo Jojo / The Plan Backfires - John Debney
 * 16) Don’t You Realize What You’ve Done? /The Powerpuff Girls Split Up - John Debney
 * 17) A Lonely Purpose - John Debney
 * 18) Junior’s nightmare / Morbucks’ journey - John Debney
 * 19) 1998 Blossom and 2016 Blossom – John Debney
 * 20) Blossoms Kidnapped - John Debney
 * 21) Bliss Gets A Warning from the Girls – John Debney
 * 22) Two Mojo Jojos – John Debney
 * 23) Save It For The Jury, Bloss – John Debney
 * 24) Townsville Hall / Sad Bliss / Guilty Buttercup – John Debney
 * 25) Back to the 1998-2005 Universe – John Debney
 * 26) Rescuing The Blossoms / 2016 Blossom and Bliss Reconcile - John Debney
 * 27) The Powerpuff Girls of Infinite Earths - John Debney
 * 28) Final Battle - John Debney
 * 29) The Townsvilles Are Saved - John Debney
 * 30) Teen Titans – John Debney
 * 31) A Promise To Keep Saving Townsville - John Debney

Remixes of Bonnie McKee's "American Girl"

 * American Girl (DJ Linuxis Remix) - Bonnie McKee
 * American Girl (Steve Aoki Remix) - Bonnie McKee
 * American Girl (Liam Walds Remix) - Bonnie McKee
 * American Girl (Oliver Remix) - Bonnie McKee
 * American Girl (Acoustic Version) - Bonnie McKee

Songs featured in the movie

 * Wonderful Life (Mi Oh My) (from “The Angry Birds Movie”) – Matoma
 * Señorita – Camila Cabello, Shawn Mendes
 * bad guy – Billie Eilish
 * Game Time – Flo Rida, Sage the Gemini
 * On Top of the World - Imagine Dragons
 * TALK TALK (Japanese Version) - Wengie, eill, David Amber
 * Brokenhearted – Karmin
 * Best Love Song – T-Pain, Chris Brown
 * Portals (from “Avengers: Endgame”) - Alan Silvestri
 * Butter – BTS
 * Party Rock Anthem – LMFAO, Lauren Bennett, GoonRock
 * Battle Royale (from “The LEGO Batman Movie”) - Lorne Balfe
 * I Am A Gummy Bear – Gummibär

Songs from the trailers

 * Let’s Go - Tiësto, Icona Pop (Teaser Trailer; TV Spots)
 * Do It Like This – Daphne Willis (Official Trailer; TV Spots)
 * I Cry – Flo Rida (Official Trailer; International Trailer; Final Trailer; TV Spots)
 * Can’t Get Enough – Becky G, Pitbull (International Trailer; TV Spots)
 * Who’s Got the Power? – Tacocat (Final Trailer; TV Spots)
 * Ho Ho Ho - Sia (Christmas TV Spots)

Release
The film was theatrically released in North America and the Philippines on November 22, 2024 in 2D, 3D, IMAX, IMAX 3D, RealD 3D, Dolby Cinema, and 4DX.

A teaser trailer was released online on October 1, 2023. The film’s first official trailer was released on April 3, 2024. It was followed by a second trailer on July 1, 2024, and one month later, the third was released on August 10, 2024, until then an international trailer came out on August 31, 2024. The final trailer was released was released on September 27, 2024.

Marketing tie-ins
The brands that partnered with The Powerpuff Girls: The Movie: Generations include McDonald's for Happy Meal toys, Coca-Cola, Nestlé, and Kellogg's for their breakfast cereals, Unilever for all their worldwide brands, Firto-Lay, PureFoods for Tender Juicy Hotdog brands, Smart Communications, Inc., Oreo Cookies, Chips Ahoy!, Tic Tac, Xfinity, Dish Network, DIRECTV (Satellite), and Sky UK. LEGO sets were also made to promote the film. The Funko POP! Figures will be the same as the original ones, but with Blisstina Utonium and Jared Shapiro added.

Spin Master reproduced the 8” Blossom, Bubbles, and Buttercup plush toys, with a new 8” Bliss plush added. They also manufactured several playsets based on the film.

There was also a game app based on the film alongside Warner Bros. Games, Warner Bros. Interactive Entertainment, and Cartoon Network Games.

There was also an Angry Birds Friends tournament as a promotional tie-in for the film. The tournament is called Angry Birds Friends X The Powerpuff Girls: The Movie: Generations. Players can launch the birds, destroy the cages, pop the pigs, and free the main, parallel, and alternate versions of the Powerpuff Girls.

Devsisters Corporation partnered with Warner Bros. to collaborate Cookie Run: Kingdom with The Powerpuff Girls: The Movie: Generations. The collaboration served as a promotional tie-in for the film.

There were also two lyric videos for “American Girl” by Bonnie McKee and “Me & My Girls” by Fifth Harmony, both are which are from The Powerpuff Girls: The Movie: Generations. Both were on all of the Warner Bros. YouTube channels worldwide. The music videos for these two songs were edited and features clips from The Powerpuff Girls: The Movie: Generations.

SuperMarioLogan made a deal with Warner Bros. to produce five new SML videos for YouTube featuring Blossom, Bubbles, Buttercup and Bliss to promote The Powerpuff Girls: The Movie: Generations. Amanda Leighton, Kristen Li, Natalie Palamides, and Olivia Olson made a guest appearance in the SML movie, reprising their roles as puppet versions of Blossom, Bubbles, Buttercup, and Bliss for the new SML videos.

SMG4 and Warner Bros. reached a deal to produce 6 new SMG4 videos for YouTube featuring Blossom, Bubbles, Buttercup and Bliss to promote The Powerpuff Girls: The Movie: Generations. Luke Lerdwichagul and the team at Glitch Productions made 3D models of Blossom, Bubbles, Buttercup and Bliss, which were then ported over to Garry’s Mod for the new SMG4 videos. Even though Amanda Leighton, Kristen Li, Natalie Palamides, and Olivia Olson provided voice lines for Blossom, Bubbles, Buttercup and Bliss, they did not actually speak sometimes like other characters (Mario, Luigi, and some other SMG4 characters), and only said some small lines or sounds. However, at other times, they do speak like some characters do (SMG4, Meggy, Bob, Fishy Boopkins, etc).

There was also an exclusive The Shop: Uninterrupted featurette featuring LeBron James, Maverick Carter, Blossom, Bubbles, Buttercup, and Bliss. In the clip, Blossom, Bubbles, Buttercup and Bliss discuss The Powerpuff Girls: The Movie: Generations with LeBron and Maverick.

Short film
The film's theatrical release was preceded by a LEGO Movie short film titled Santa’s Little Helpers: A LEGO Movie Short. In the short film, Emmet and his Master Builder friends, Wyldstyle, Unikitty, Benny, and MetalBeard, having accidentally arrived at the North Pole, make the most of the situation by trying to become elves.

The short film stars the voices of:


 * Chris Pratt as Emmet
 * Elizabeth Banks as Wyldstyle
 * Alison Brie as Unikitty
 * Charlie Day as Benny
 * Nick Offerman as MetalBeard
 * James Adomian as Head Elf
 * Tom Kenny as Santa Claus
 * Eden Sher as Baby Reindeer
 * Alan Tudyk as Adult Reindeer
 * Dana Davis, Eden Sher, and Alan Tudyk as Elves

The short's running time is 4 minutes, and its end credits song is "Everything Is Awesome (Christmas Remix)" by Jo Li.

Home Media
The film was released on Cartoon Network On Demand (Censored/edited version), the Cartoon Network App (Censored/edited version), premium-video-on-demand (where it was available for rent on Apple TV (Uncensored version), Prime Video (Uncensored version), Vudu (Uncensored version), Google Play (Uncensored version), YouTube (Uncensored version), Dish Network, DIRECTV, and Xfinity), and also streaming exclusively on HBO Max (Uncensored version) on January 14, 2025, and on Ultra HD Blu-ray, Blu-ray and DVD (all use the Uncensored version like HBO Max) on February 6, 2025 by Warner Bros. Home Entertainment. It includes deleted scenes, the filmmakers commentary, the "Behind-The-Puffs" featurette, the outtakes, the nine digital shorts from Seasons 1 and 2 of the 2016 reboot (Air Buttercup, Bubbles' Beauty Blog... but on Video, Run Blossom Run, Ping Pong Z, Bubbs & Donny Get the Mail, Bedtime, Mojo Builds a Shelf, I’ll Be Bake, and Blissfully Unaware), the LEGO Movie short Santa’s Little Helpers, and a sing-along version. It was also included in the Powerpuff Girls Complete Series DVD. The film made its television premiere on Cartoon Network on May 3, 2025, but any uses of the F-word and sh-word were edited out,

In Southeast Asia, the film was released on Cartoon Network on September 24, 2025 and it was simulcast on Boomerang, Oh!K, Warner TV, DreamWorks Channel, HBO, and HBO Family.

Box Office
The Powerpuff Girls: The Movie: Generations grossed $858.3 million in the United States and Canada, and $1.939 billion in other territories, for a worldwide total of $2.798 billion, becoming the highest-grossing film of all time in the United States and Canada. It is the fifth-highest-grossing film of all time worldwide.

The film had a worldwide opening of $1.2 billion. It was also the fastest film ever to eclipse the $1 billion and $1.5 billion mark, doing so in just five days and eight days, respectively. Deadline Hollywood estimated the film would break even just five days after its release, which is "unheard of for a major studio tentpole during its opening weekend". The website eventually calculated the final net profit of the film to be $890 million, accounting for production budgets, marketing, talent participations, and other costs, with box office grosses, and ancillary revenues from home media, placing it first on their list of 2024's "Most Valuable Blockbusters".

On December 7, the film's earnings at the global box office became the fastest film ever to gross $2 billion worldwide, amassing the amount in only 11 days. It also became the fifth film to surpass this threshold, and the second film to surpass the threshold of $2.5 billion, doing so in just 20 days.

United States and Canada
The Powerpuff Girls: The Movie: Generations set the records on Fandango for most tickets sold by an animated film in that frame. The film was projected to gross $200–250 million domestically during its opening weekend, although some insiders saw those figures as conservative and expected a $260–300 million debut. By the week of its release, domestic estimates had risen to $260–270 million, with some insiders still suggesting a $300 million debut was possible. The film played in 4,662 theaters, 410 of which were in IMAX. The Powerpuff Girls: The Movie: Generations earned $357.1 million in its opening weekend. It also set records for Friday ($157.5 million, including $60 million from Thursday night previews), Saturday ($109.3 million), and Sunday ($90.4 million) totals, as well as was more of a total gross alone than the previous box office high of all films combined ($314 million). The film then made $36.9 million on Monday and $33.1 million on Tuesday, both the third-highest of all time. In its second weekend the film made $147.4 million (the second-best sophomore frame ever) for a 10-day total of $621.3 million. It was the fastest film to ever pass the $600 million milestone. The following week, the film grossed $64.8 million, the fourth-best third weekend ever. It also passed the $700 million mark. It made $17.2 million the following weekend (and a total of $22.3 million over the four-day Memorial Day frame), crossing the $800 million threshold domestically. During the re-release, which occurred over its tenth weekend, the film was added to 1,040 theaters and made $6.1 million, an increase of 207% from the previous weekend. In its thirteenth weekend the film made $1.2 million.

Other territories
Internationally, The Powerpuff Girls: The Movie: Generations was projected to gross around $680 million over its first five days for a global debut of $850–950 million. The film was initially projected to gross $250–280 million in China in its opening weekend, but made a record $107.5 million (RMB 719 million) in the country on its first day, including $28.2 million (RMB 189 million) from midnight, 3 AM and 6 am screenings. Due to the record-breaking first day, partnered with word of mouth (with a 9.1 on local review aggregator Douban and a 9.3 on ticket website Maoyan), debut projections were increased to over $300 million. Overall, the film made $169 million on the first day from international countries, the highest total of all time. Its largest markets after China were India ($9 million), South Korea ($8.4 million; the largest non-holiday single day gross ever), Australia ($7.1 million), France ($6 million), and Italy ($5.8 million). Like domestically, the film ended up over-performing and debuted to $866 million overseas. Its largest markets, every one of which set the record for best-ever opening in the country, were China ($330.5 million; RMB 2.22 billion), the United Kingdom ($53.8 million), South Korea ($47.4 million), Mexico ($33.1 million), Australia ($30.8 million), Brazil ($26 million), Spain ($13.3 million), Japan ($13 million), and Vietnam ($10 million). It also made $21.6 million over its first four days in Russia after a delay of its premiere that was caused by the Russian government.

In its first week, the film's top five largest international markets were China ($459.4 million), the United Kingdom ($68.2 million), South Korea ($60.3 million), Mexico ($48.6 million), and India ($40.9 million). A week after its release, it became the highest-grossing foreign film of all time in China and India. In its second weekend the film's running total passed $1.569 billion from international markets.

The film's top international markets were China ($629 million), United Kingdom ($115 million), South Korea ($105 million), Brazil ($86 million), and Mexico ($78 million).

Critical response
On review aggregation website Rotten Tomatoes, the film holds an approval rating of 100% based on 421 reviews, with an average rating of 10/10. The website's critics consensus reads, "Heartwarming, funny, beautifully animated, and filled with returning voice actors, returning characters, and musical numbers, The Powerpuff Girls: The Movie: Generations really does have the power and brings the family together." Metacritic, which uses a weighted average, assigned the film a score of 84 out of 100 based on 57 critics, indicating "universal acclaim." Audiences polled by CinemaScore gave the film an average grade of "A+" on an A+ to F scale, while those at PostTrak gave it an overall positive score of 100%, a 100% "definite recommend," and a 5 star rating.

The film received a four-star rating from Matt Zoller Seitz of RogerEbert.com, who wrote, "This film is a massive improvement over the 2016 reboot, as there is no cringe in this film." The Washington Post's Ann Hornaday also gave the film 5 out of 5 stars and praised its, "visually dazzling concoction of wily schemes and daring adventures", as well as achieving, "a continuation of Cartoon Network's theatrical reputation." Peter DeBruge of Variety wrote, "The Powerpuff Girls: The Movie: Generations ushered in the era of traditionally animated cartoon features, and this sequel wraps up the saga beautifully." The Daily Telegraph 's Robbie Collin wrote, "The Powerpuff Girls: The Movie: Generations reaffirms that the Warner Animation Group, at their best, are like no other animation studio around." Writing for Variety, Peter Debruge wrote, "The 2016 Girls have been improving on their singing, and their 1998 counterparts gave them the power again. This film wins back what made the original series special."

The film also gained lots of positive feedbacks from many fans of the original series, with one saying "This film is a massive improvement over the 2016 reboot. Warner Animation Group should make more animated films based on the 2016 reboot." Another fan of the original series wrote, "Warner Animation Group should continue the adventures of Blossom, Bubbles, Buttercup, and Bliss."

Accolades
The Powerpuff Girls: The Movie: Generations won Best Animated Feature Film at the 82nd Golden Globe Awards, and won the same award at the 30th Critics' Choice Awards and the 97th Academy Awards, among several other awards and nominations. The film appeared on many critics' top ten lists. According to Metacritic it appeared in first place on 5 lists. Critics at New York Magazine listed it at 9 on their list of the best films of the decade. It also won the Razzie Redeemer Award at the Golden Raspberry Awards.

Trivia

 * The first installment of Warner Animation Group's Cartoon Network Cinematic Universe.
 * The first time the 2016 reboot got a feature film.
 * It is revealed that the 1998 Powerpuff Girls and 2016 Powerpuff Girls are from separate universes.
 * Nick Jennings and Bob Boyle replace Craig McCracken from the first film, though McCracken serves as one of the executive producers of the film.
 * John Debney replaces James L. Venable from the first film.
 * The film serves as the series finale of the 2016 reboot.
 * The narrator never says "The City of Townsville" at the beginning of the movie, but Bubbles reads these words on the papers before the curtains even open.
 * The scene where 2016 Blossom and Bliss sang "Brokenhearted" by Karmin while fighting off Mojo Jojo's evil primates is similar to the scene where Katie Mitchell and Rick Mitchell sang "Live Your Life" by Rihanna and T.I. while fighting off the PAL Max Prime robots from the 2021 Netflix and Sony Pictures Animation film The Mitchells vs. the Machines.
 * The Powerpuff Time Machine is the third character for Olivia Colman to voice in animated film, after PAL from The Mitchells vs. the Machines (2021) and Donka from Ron's Gone Wrong (2021).
 * Violet is Abbi Jacobson's third animated character after Nya from The LEGO Ninjago Movie (2017) and Katie Mitchell from The Mitchells vs. the Machines (2021).
 * Bunny is Awkwafina's sixth animated character after the Quail from Storks (2016), Courtney from The Angry Birds Movie 2 (2019), Otto from The SpongeBob Movie: Sponge on the Run (2020), Sisu from Raya and the Last Dragon (2021), and Ms. Tarantula from The Bad Guys (2022).
 * Bloom is Rachel Bloom's fourth animated character after Silver from The Angry Birds Movie 2 (2019), Queen Barb from Trolls World Tour (2020), and Op from Extinct (2021).
 * Unlike the first Powerpuff Girls movie (which was rated PG), this movie is rated PG-13 for strong language because in a scene, Blossom said 'fuck' one time in a non-sexualized way. According to the Motion Picture Association film rating system, the F-word can be said once in a PG-13 film as long as it’s said as an expletive. If it’s said more than once or if it’s used in a sexual context or manner, it automatically incurs an R rating. Additionally to 1 use of 'fuck,' there are also 2 uses of 'shit,' 4 uses of 'hell,' 2 uses of 'damn,' and one use of 'crap,' although the last 3 mentioned are mild language.
 * This is the final appearance of the narrator in the 2016 reboot storyline, though he returned in the 1998 series revival. He also returned in the sequel.
 * Bunny’s voice in the film had inspiration from Huggy’s voice from Bob Boyle and Nick Jr.’s Wow! Wow! Wubbzy! (another show Lara Jill Miller worked on with Bob Boyle)
 * This film premiered the day exactly 5 years after Frozen II (2019) released theatrically.
 * During production of the film, it was announced that a Minions TV Series was in the works.
 * The Powerpuff Girls from Bleedman's PPGD webcomic also got transported to the 2016 universe.
 * Craig McCracken, the creator of the original Powerpuff Girls series, said that he approved this movie, along with Seasons 4, and 5 of the 2016 reboot.
 * Months before production on the film finished, Warner Animation Group confirmed that a third The Powerpuff Girls film was in the early stages of development, which is set to be based on Craig McCracken’s Powerpuff Girls reboot instead of the 2016 reboot, and it’s also set to be produced in association with Universal Pictures and Illumination. This would mean Catherine Cavadini, Tara Strong, and Elizabeth Daily are the respective voices of Blossom, Bubbles, and Buttercup instead of their 2016 voice actresses. But this also means Bliss isn't part of the film because she did not appear in the 1998 series nor the revival by Craig McCracken.
 * Alongside the 2016 Powerpuff Girls series collaborators, as well as Phil Lord, Christopher Miller, Daron Nefcy, Chris DeFaria, Pernelle Hayes, Eyal Podell, Jonathon E. Stewart, Allison Abbate, John Requa, Glenn Ficarra, Nicholas Stoller, and Craig McCracken, certain crew members who worked on Disney’s Gravity Falls, Star vs. the Forces of Evil, Amphibia, The Owl House, Big City Greens, Nickelodeon’s SpongeBob SquarePants, The Loud House, and 20th Television Animation’s Family Guy, American Dad!, Futurama, and Bob’s Burgers were also involved with the film.

Cameo appearances

 * An image of Ultrakatty from The LEGO Movie 2: The Second Part is seen on one of the lockers.
 * Migo, Meechee, Gwangi, Fleem, and Kolka from Smallfoot can be seen as plush toys in the Powerpuff Girls’ room.
 * Diamond Destiny from Storks is seen on a baby carriage when Bubbles sings "Important Things In Life".
 * Wolf Pack leaders Alpha and Beta from Storks appear as bobbleheads on one of the vehicles.
 * Krypto, Ace, Chip, Merton, and PB from DC League of Super-Pets make a cameo on a sidewalk.
 * A Townsville citizen wears the same robe as the Stonekeeper.
 * Harley Quinn's mallet from The LEGO Batman Movie is seen inside one of the lockers.
 * The Ultimate Ultimate Weapon chest from The LEGO Ninjago Movie made a cameo appearance in the Girls' closet.
 * A poster for The LEGO Movie 2: The Second Part is seen at the back of the bus.
 * Blue Falcon (Brian) and Dynomutt appear as two figurines among Bubbles’ 3D printed models of the Space Tow Truck characters.
 * Pigeon Toady appears a figurine in the Powerpuff Girls’ room.
 * LeBron James from Space Jam: A New Legacy makes a cameo appearance as a bobblehead in the school bus.
 * Butch from Tom & Jerry can be seen in a "Hang In There, Baby" poster.
 * Emmet, Wyldstyle, Unikitty, Benny, MetalBeard, Batman, and Vitruvius from The LEGO Movie can be seen as regular LEGO figures among Bubbles’ 3D printed models of the Space Tow Truck characters.
 * Wile E. Coyote and the Road Runner from Coyote vs. Acme make a cameo appearance in another scene during the “Townsville Is Where We Belong” song sequence.
 * The books The Cat in the Hat, Oh, the Places You'll Go!, The Ice Dragon, Toto, The Dog-Gone Amazing Story of The Wizard of Oz, Wed Wabbit, and That Christmas appear in a bookshelf.
 * Rex Dangervest from The LEGO Movie 2: The Second Part makes a cameo as a keychain on Professor Utonium’s car keys.
 * The Mystery Machine from Scoob! makes a cameo appearance parked near the Derbytantes’ lair.
 * Pete from Space Jam: A New Legacy makes a cameo appearance as a hanging accessory on the mirror on one of the vehicles.
 * A poster of The LEGO Movie can be seen in the 2014 Powerpuff Girls' house.
 * A scene from The LEGO Batman Movie can be shown on the screen of the Townsville Multiplex during the final battle scene.
 * Finn and Jake from the untitled Adventure Time film appear on one of the picture frames in the Utonium House.
 * Gumball and Darwin from the untitled Amazing World of Gumball film make cameo appearances on one of the picture frames in the Utonium House.
 * Unikitty, Puppycorn, Dr. Fox, Hawkodile, and Richard from the untitled UniKitty! film make a cameo appearance on one of the picture frames in the Utonium House.
 * A picture of the DC Super Hero Girls is seen on one of the picture frames in the Utonium House.
 * A Marceline the Vampire Queen plush toy is seen being hugged by Bliss in a scene where 2016 Bubbles saw Bliss crying.
 * Mordecai and Rigby make a cameo appearance as bobbleheads on Ms. Keane’s car.
 * Steven Universe and the Crystal Gems make a cameo appearance as figurines on Bliss’ desk.
 * Robin, Starfire, Beast Boy, Cyborg, Raven, and Bumblebee Teen Titans Go! appear as figurines on one of Blisstina’s shelves.
 * Posters of The LEGO Movie, Storks, The LEGO Batman Movie, The LEGO Ninjago Movie, Smallfoot, The LEGO Movie 2: The Second Part, Scoob!, Tom & Jerry, Space Jam: A New Legacy, DC League of Super-Pets, The Powerpuff Girls Movie, Regular Show: The Movie, Steven Universe: The Movie, We Bare Bears: The Movie, and Ben 10 Versus The Universe: The Movie appear in the Townsville Multiplex (inside and outside) when the people are running outside the building in the final battle scene.
 * Grizz, Panda, and Ice Bear from We Bare Bears can be seen running (in bear stack form) outside the Townsville Multiplex during the final battle scene.
 * Nito, Glob, Wedge, and Itty, mascots of Cartoonito, make a cameo appearance on a poster on a wall.
 * Posters of Jessica’s Big Little World and We Baby Bears appear on a glass window.

Sequel
Warner Animation Group confirmed that a sequel to The Powerpuff Girls: The Movie: Generations was in the early stages of development, which is to produced in association with Universal Pictures and Illumination.

Follow-up television series
The Powerpuff Girls: Tales from the City of Townsville is an HBO Max original animated musical television series co-produced with Cartoon Network Studios. It is the sequel to the 2016 iteration of The Powerpuff Girls. Many of the same collaborators of the 2016 reboot of The Powerpuff Girls will be involved with this new series, and the spin-offs. The series takes place after the events of the 2016 iteration of The Powerpuff Girls and the 2024 film The Powerpuff Girls: The Movie: Generations. The series was animated at Sunmin Image Pictures, which also provided the animation for the four spin-offs. Like Seasons 4, 5, and 6 of the 2016 series, every episode had 1 or 2 songs (3 songs for double length episodes) which last 1 minute and 45 seconds.

Set after the events of The Powerpuff Girls: The Movie: Generations, Blossom, Bubbles, Buttercup, and Blisstina: four girl superheroes have recently reduced crime and now live a normal life, although they still have their powers. Even so, they still save Townsville whenever they are needed, because a lot of crime eventually comes back. The Powerpuff Girls: Tales from the City of Townsville is the next chapter in the Powerpuff Girls’ adventures, and focuses on their everyday lives and musical adventures.

The series premiered on Cartoon Network and HBO Max on May 28, 2025.

 It's Blossom!
It's Blossom! is an HBO Max original animated series produced by Cartoon Network Studios.

Blossom Powerpuff stars in her own show, with new songs, new friends, new life, and new fun video chats to have with real people and kids, and even teens!

Alongside The Powerpuff Girls: Tales from the City of Townsville, the series premiered on Cartoon Network and HBO Max on May 28, 2025.

 Bubbles' World
Bubbles' World is an HBO Max original animated series produced by Cartoon Network Studios.

Bubbles’ World follows everyone’s favorite bubbly Powerpuff Girl at home in her room as she hosts an imaginary variety show that comes from the bizarre and hysterical depths of her own brain.

Alongside The Powerpuff Girls: Tales from the City of Townsville and It's Blossom!, the series premiered on Cartoon Network and HBO Max on May 28, 2025.

The Buttercup Show
The Buttercup Show is an HBO Max original animated series produced by Cartoon Network Studios.

Not much is known about the new series, but what is known is that Buttercup will be voiced by Natalie Palamides.

Alongside The Powerpuff Girls: Tales from the City of Townsville, It's Blossom!, and Bubbles' World, the series premiered on Cartoon Network and HBO Max on May 28, 2025.

Blisstina's Club
Blisstina's Club is an HBO Max original animated series produced by Cartoon Network Studios.

Is there anyone who can say they never wished they could be a fly on the wall inside their idols’ homes? Particularly when we’re talking about Blisstina (voiced by Olivia Olson), the cutest and most dazzling popstar on the planet, and when the mobile home in question is the Blissmobile, a super stylish party on-the-go during a world tour. A mobile home is just the thing for Blisstina, since no neighbor can stand the ruckus created by this crew of friends who approach every day like it’s a party. Good thing that Blisstina’s friends, Barasia, Bulaklak, Bloom, and Bunny (who is the same height as Blossom, Bubbles, and Buttercup) in addition to her sisters, Blossom, Bubbles, and Buttercup, are there to remind her about what really matters. Juggling domestic issues, spectacular shows and epic drama, Blisstina’s set to find out that being with those you care about is the best part of any trip.

Alongside The Powerpuff Girls: Tales from the City of Townsville, It's Blossom!, Bubbles' World, and The Buttercup Show, the series premiered on Cartoon Network and HBO Max on May 28, 2025.

Transcript
Main article: The Powerpuff Girls: The Movie: Generations/Transcript

Credits
Main article: The Powerpuff Girls: The Movie: Generations/Credits