The Powerpuff Girls: The Movie: Generations

The Powerpuff Girls Movie 2: Generations is a 2024 American animated superhero musical film produced by the Warner Animation Group. The film is directed by series developers Nick Jennings and Bob Boyle, from a screenplay by Alicia Chan, Grace Kraft, and Jaydeep Hasrajani and a story by Jake Goldman, Haley Mancini, Eyal Podell, and Jonathon E. Stewart. A standalone sequel to The Powerpuff Girls Movie, it is based on The Powerpuff Girls created by Craig McCracken, the one-reel film Whoopass Stew by Craig McCracken, the 2014 special Dance Pantsed by David P. Smith, the anime Powerpuff Girls Z by Megumu Ishiguro, and the 2016 reboot developed by Nick Jennings and Bob Boyle, and partially takes place concurrently with The LEGO Movie 3: A Powerpuff Adventure. The film stars Amanda Leighton, Kristen Li, Natalie Palamides, Olivia Olson, Bill Hader, Zach Woods, Nick Kroll, Jennifer Hale, Kate Higgins, Tom Kenny, Roger L. Jackson, Cathy Cavadini, Tara Strong, and E.G. Daily. This film serves as the series finale of the 2016 reboot of The Powerpuff Girls.

The Powerpuff Girls Movie 2: Generations was theatrically released on November 22, 2024 by Warner Bros. Pictures, in 2D, 3D, IMAX, IMAX 3D, RealD 3D, Dolby Cinema, and 4DX. The film received positive reviews aimed at the animation, style, voice acting, soundtrack, and musical numbers, with several positive comparisons as a combination of Phineas and Ferb the Movie: Across the 2nd Dimension, Avengers: Endgame, Frozen II, Spider-Man: Into the Spider-Verse, and Teen Titans Go! vs. Teen Titans. It also crossed the billion dollar mark, grossing $1.073 billion against a budget of $90 million and became the highest-grossing film of 2024 and the highest-grossing film of all time.

The film is dedicated to Chuck McCann, voice of the Amoeba Boys in the classic series and 2016 reboot episode Viral Spiral, who died on April 8, 2018.

Synopsis
Blossom, Bubbles, and Buttercup have been saving Townsville for many years. But when a portal that the Professor recently invented starts malfunctioning, the Girls discover their past selves: the 1998-2005 Powerpuff Girls! To save their dimensions from being destroyed, they must team up with the 1998-2005 Girls to go through other dimensions, while also meeting their other past selves, such as the 2014 Girls, their 2006-2007 PPGZ's, and the 1992 Girls.

Plot
The film begins with a stage with the red curtains above. Bubbles thanks the audience for coming as she tells us that this is the story of how the Powerpuff Girls met their past selves and teamed up with them. She then starts reading the opening quotes (from the 1998-2005 series) on her paper. As she reads them, the curtains open to reveal a skyline of Townsville.

Nineteen years after defeating Mojo Jojo (Roger L. Jackson) and his evil primate gang, Powerpuff Girls Blossom (Amanda Leighton), Bubbles (Kristen Li), and Buttercup (Natalie Palamides) discover what it feels like to work together ("Townsville Is Where We Belong"), while also meeting up with Jared, Barry, the Derbytantes, and other classmates, as well as friendly Rowdyruff Boys Brick (Bill Hader), Boomer (Zach Woods), and Butch (Nick Kroll). The next day, Professor Utonium (Tom Kenny) invents a time portal and the Girls are amused. Afterwards, Amoeba Boys Bossman (DJ Khaled), Slim (Will Arnett), and Junior (Lil Rel Howery) break in and rewire the circuits of the portal, thus making it malfunction and start releasing the Powerpuff Girls' past selves.

On the way to school, Bubbles wanders around the streets, thinking about the important things in her lifetime ("Important Things In Life"). The Girls enter the school, and Bubbles says that the school is really lit, as Blossom gets a crush on Jared. Buttercup asks Blossom if she's gonna talk to him, and Blossom tells her that she hasn't decided yet.

At lunch, Blossom talks to her sisters about the past of Townsville, in which she learned about. Bubbles tells Blossom that wisdom, humility, and honesty are the three things that she is looking for, even though she is the cute one. Brick, the leader of the friendly Rowdyruff Boys, calls Blossom, and he tells her that he found out about the other versions of the Powerpuff Girls. He also tells her that he got a footage of the Amoeba Boys tampering with the Professor's portal. At the Girls' table Bubbles tells Buttercup that the past comes before the present. Blossom later comes back to the table and tells Bubbles and Buttercup that there really are other versions of the Powerpuff Girls in main, parallel, and alternate universes.

Later, when the Girls got back from school, they discover that the portal had been malfunctioning. After trying to fix it, the portal inadvertently brings in their 1998 animated selves (Cathy Cavadini, Tara Strong, and E.G. Daily). They tell them that nothing is what is seems in all the dimensions, and that the now-powerful Giant Fishballoon (Kevin Michael Richardson) is coming back to destroy them. The next day, the six girls fly over to their school, only for Miss Keane (Jennifer Hale) to realize that there were six Powerpuff Girls in the school, leaving her confused. They then fly over to the Mayor’s office, only for the Mayor (Tom Kenny) to get confused about their differences and get his assistant Miss Bellum to get them out. Back at home, the Professor is concerned about their differences and looks, as well as why the portal was malfunctioning, and tells the six girls that their universes are getting destroyed. So he tasks the six girls to get more of their old selves to put together a team.

In their room, they think of a plan to stop the Fishballoon by joining forces with each other ("Getting The Team Together"). They later sneak into the Derbytantes' lair, thus sending the 1998 Girls to sneak up on Maylyn (Kate Higgins), who later discovers that there are two Buttercups, two Blossoms, and two Bubbleses. They later talk about why the portal had been malfunctioning. Bubbles tells the Derbytantes the story about how the Professor created them and how the Girls and Mojo Jojo became enemies after he filled all the primates with Chemical X, as well as how they were dubbed "The Powerpuff Girls". Once the six Girls got home, the portal brings in the 2014 Girls (also Cathy Cavadini, Tara Strong, and E.G. Daily), who offer to help them with their mission.

The nine meet up with Blisstina Utonium (Olivia Olson), who shows them the Orb of Main, Parallel, and Alternate Universes (“A Beautiful Life”). The ten girls fly to different universes with a time machine: first the 1992 universe, then the 1998-2005 universe, the 2014 universe (“What We Did In The Past”), and finally the Powerpuff Girls Z universe.

Mojo Jojo, Fuzzy Lumpkins (Jim Cummings), Princess Morbucks (Haley Mancini), the Amoeba Boys (Arnett, Khaled, and Howery), the Gangreen Boys (Tom Kenny, Jeff Bennett), HIM (Sam Marin), Duplikate (Jill Talley), Bianca Bikini (Lily Vonnegut), Barbara Bikini, the Sporde (Ben Diskin), Silico (Jason Spisak), Gothra (Conrad Vernon), Sedusa (Kristen Wiig), Packrat (also Spisak), Bernie Bernstein (Tom Kenny), Manboy (Maurice LaMarche), the Broccoloids (Jeff Bennett), Chelsea (Kirby Howell-Baptiste), and the other villains all travel to the 1998-2005 dimension, and make a deal with the Fishballoon to defeat the Girls once they show up.

The Girls make it to the 2016 universe. They face Mojo and his gang, and try to battle him, but they are all outnumbered. Blossom tries to unleash the other versions of the Powerpuff Girls using the Orb of Alternate Universes, but the other Girls stop her from doing so. Before the villains could easily defeat the Girls, Bliss defends them with her telekinesis, thus teleporting to the junkyard and taking the Girls with her. After an argument between Bliss and 2016 Blossom, the Girls all split up.

2016 Bubbles gets heartbroken about what 2016 Blossom did to them and starts crying. 2016 Buttercup comforts her, and tells her that there's no end of friendship ("We Don't Want To Be Far Apart") and 2016 Bubbles feels better and hugs 2016 Buttercup.

Meanwhile, a sad 2016 Blossom is sitting alone in the middle of the junkyard. She starts crying because of the argument she and Bliss had earlier. 1998 Blossom comes to her and tells her that it is never too late to do the right thing (“The Right Thing To Do”). Unfortunately, Princess Morbucks kidnaps the Blossoms and takes them back to the 1998-2005 universe, sending them to Mojo Jojo’s lair. 2016 Bubbles, 2016 Buttercup, 1998 Bubbles, and 1998 Buttercup discover that the Blossoms have been kidnapped, and manage to tell Bliss about it.

Heartbroken, Bliss doubts her selfish desire about the other versions of the Powerpuff Girls (“Selfless”), and realizes that Blossom was right: the best way to defeat them is to unleash the Powerpuff Girls of Infinite Earths. The Bubbleses and Buttercups arrive and tell Bliss that the Blossoms have been kidnapped. The other Powerpuff Girls arrive too, and they fly to the 1998-2005 universe.

Meanwhile, 2016 Mojo Jojo reveals to the Blossoms that he is now working for 1998 Mojo Jojo. The Mojo Jojos activate the killing machine to start erasing the Blossoms forever. The Girls arrive and rescue the two from the machine. The Buttercups unplug the machine. 2016 Blossom and Bliss reconcile and the Girls promise to work together, this time as a team, and fly back to the 2016 universe.

2016 Blossom gives up her leadership to Bliss, who uses the Orb of Main, Parallel, and Alternate Universes to form the “Powerpuff Girls of Infinite Earths”: the Powerpunk Girls, the Powerpup Girls, the Powerpuff Animals (Blossom as a walrus, Bubbles as a bee, and Buttercup as a flamingo), the 1920s Cartoon Girls, the dancing robotic Powerpuff Girls, the Powerpuff Girls Doujinshi (Rachel Matthews, Ariel Winter, and Jillian Bell), Bunny (Awkwafina), Bell (Kristen Bell), Bloom (Rachel Bloom), Bullet (Kate Micucci), and many other versions of the Girls. They easily overpower the Villains, and then, the Powerpuff Girls activate Dynamo to take out the bad guys. When Mojo Jojo and his crew have surrounded the Girls, the Professors from other universes, as well as the Rowdyruff Boys, the Derbytantes, and everybody else, come to their rescue, with the Derbytantes finally taking down the bad guys. Then, Mojo Jojo's evil primates arrive, but Bliss and 2016 Blossom work together to fight all the primates while singing Fifth Harmony's "That's My Girl", joined by the 2016 Bubbles, 2016 Buttercup, the 1998 Girls, the 2014 Girls, the PPGZ girls, Professor Utonium, Maylyn, and the Rowdyruff Boys. The Girls finally defeat Mojo Jojo; however, 2016 Blossom sacrifices herself to defeat the Giant Fishballoon by plummeting him onto the ground, causing a huge explosion.

All of the Girls, including Bliss, Professor Utonium, Maylyn, and the Rowdyruff Boys look for 2016 Blossom until Brick finds her unconscious body. Bliss tries to wake 2016 Blossom up, but it was no use; this led to Bliss crying softly and embracing 2016 Blossom's body. 2016 Blossom then wakes up, and reveals to Bliss and the others that the Fishballoon had already been shrunken. Bliss was happy that 2016 Blossom did the right thing, and 1998 Blossom says that she was proud of 2016 Blossom. Bliss then uses the Orb to send him to the Teen Titans GO! universe.

With the Townsvilles finally at peace, all of the Girls are sent home to their respective dimensions. Robin, Starfire, Beast Boy, Cyborg, and Raven arrive and reveal to the Girls that The Fishballoon had tried to take over the Townsvilles, and Blossom knows the right location for it: the exact same zombie dimension that the Titans sent 2013 Trigon to (which he somehow escaped from). Raven opens a portal using her magic to send the Fishballoon there.

The next day, the 2016 Powerpuff Girls are glad that they don’t have to endure another multiverse-threatening crossover for at least another year, and promise to keep saving Townsville no matter what happens ("The Big Finale"). The Rowdyruff Boys now become Maylyn’s leading assistants. The Powerpuff Girls finally resume their attendance at Midway Elementary School. The narrator says “And so once again, with the help of all of their past selves and main, parallel, and alternate versions, the day is saved, thanks to: The Powerpuff Girls! Close the curtains and let the end credits roll!” And then the song ends and the curtains close ("American Girl").

In a mid-credits scene, 2016 Bubbles visits Unicorn Land and recounts the events she experienced to Donny and the unicorns.

Main Characters

 * Amanda Leighton as 2016 Blossom
 * Kristen Li as 2016 Bubbles
 * Natalie Palamides as 2016 Buttercup, Barry Mackerbacker
 * Olivia Olson as Blisstina Utonium
 * Toya Delazy voices Bliss in the African version, Wendy Ayche (Wengie) in the Australia and New Zealand version, and Alesha Dixon in the UK version


 * Bill Hader (replacing Rob Paulsen) as Brick
 * Zach Woods (replacing Rob Paulsen) as Boomer
 * Nick Kroll (replacing Roger L. Jackson) as Butch
 * Jennifer Hale as Ms. Keane and 1998 Princess Morbucks
 * Kate Higgins as Maylyn
 * Tom Kenny (replacing Tom Kane) as 2016 Professor Utonium, 1998 Professor Utonium, the Talking Dog, (reprising his role) the 2016 Mayor of Townsville, the 1998 Mayor of Townsville, The Narrator, and Mitch Mitchelson
 * Roger L. Jackson as 2016 Mojo Jojo, 2014 Mojo Jojo, and 1998 Mojo Jojo
 * Cathy Cavadini as 1998 Blossom and 2014 Blossom
 * Tara Strong as 1998 Bubbles and 2014 Bubbles
 * E.G. Daily as 1998 Buttercup and 2014 Buttercup
 * Jake Goldman as Jared Shapiro, Blossom’s love interest
 * Haley Mancini as 2016 Princess Morbucks
 * Will Arnett, DJ Khaled, and Lil Rel Howery (replacing the late Chuck McCann) as the Amoeba Boys (Slim, Bossman, and Junior)
 * Kirby Howell-Baptiste as Chelsea
 * Jim Cummings as Fuzzy Lumpkins
 * Jill Talley as Duplikate
 * Jason Kaye as Gnat
 * Lily Vonnegut as Bianca Bikini
 * Fred Tatasciore (replacing Tom Kane) as 2016 HIM and 1998 HIM
 * Tatasciore also voices Nick LaNobodyKnows


 * Dee Bradley Baker as Barbarus Bikini
 * Ben Diskin as the Sporde
 * Maurice LaMarche as Pug-Faced Paulie, Manboy
 * Charlie Puth as Charlie Chihuahua
 * Ty Dolla $ign as Dapper Dan Doberman
 * Kendrick Lamar as Al Cacone
 * Flo Rida as Poodles Canoodles
 * Kenan Thompson as Herman Shepherd
 * Wiz Khalifa as La Femme Akita
 * Mike Mitchell as Two-Tails Mulligan
 * Alex Hirsch as The Butt-Sniffer
 * Jeff Bennett as the Broccoloids, Janitaur
 * Jason Spisak as Silico, Packrat
 * Daron Nefcy as Gothra
 * Kevin Michael Richardson as the Giant Fishballoon
 * Kristen Wiig as Sedusa
 * Tom Kenny and Jeff Bennett as the Gangreen Gang, whose names are Ace, Snake, Lil' Arturo, Grubber, and Big Billy
 * Jennifer Fried as the Whoopass Girls (archival recordings)
 * Nicole Bouma as Blossom Akatsutsumi
 * Maryke Hendrikse as Bubbles Gōtokuji
 * Kelly Metzger as Buttercup Matsubara
 * Daran Norris, Eric Bauza, John DiMaggio, and Mae Whitman as miscellaneous Townsville citizens
 * Josh Fadem as Donny the Unicorn
 * Jennifer Martin as Miss Bellum
 * Yuri Lowenthal as Townsville Citizen #1
 * Seth Green as Townsville Citizen #2
 * Dwight Schultz as Lester Van Luster
 * Anais Fairweather as Jemoire
 * Kyle A. Carrozza as Harmadillo
 * Justin Roiland as a Midway Elementary student
 * Phil LaMarr as Townsville Citizen #3
 * Rob Paulsen as Rubber Bandit/Townsville Citizen #4
 * Harland Williams as HIM (Powerpuff Girls Z)
 * James Arnold Taylor as Townsville Citizen #5
 * Grey Griffin as Townsville Citizen #6
 * Roger Craig Smith as Schedulebot/Townsville Citizen #7/Bob LaGrange
 * Kath Soucie as a Midway Elemendary student
 * Eden Sher as Townsville Citizen #8/Jaylyn/Bobbysuzeraelyn/Various Derbytantes
 * Olivia Colman as Powerpuff Time Machine
 * Nick Jennings as Announcer Voice

Powerpuff Girls of Infinite Earths voices

 * Awkwafina (replacing the late Christine Cavanaugh) as Bunny
 * Kristen Bell as Bell
 * Rachel Bloom as Bloom
 * Kate Micucci as Bullet
 * Alessia Cara as Bailey
 * Tina Fey as Banana
 * Charlyne Yi as Brownie
 * Kimaya Thais as Butterfly
 * Sophie Reynolds as Bouquet
 * Abbi Jacobson as Violet
 * Rachel Matthews as PPGD Blossom
 * Ariel Winter as PPGD Bubbles
 * Jillian Bell as PPGD Buttercup
 * Chloe Bennet as Teenage Blossom
 * Dove Cameron as Teenage Bubbles
 * Yana Perrault as Teenage Buttercup
 * Sugar Lyn Beard as 1920s Cartoon Powerpuff Girls and 1930s dark and monochromatic Powerpuff Girls
 * Amanda Leighton as Walrus Blossom, Elderly Blossom, the time-travel Blossoms from the Time Dasher, and Berserk
 * Kristen Li as Bee Bubbles, Elderly Bubbles, and Brat
 * Natalie Palamides as Flamingo Buttercup, Elderly Buttercup, and Brute
 * Olivia Olson as Blister
 * Cathy Cavadini, Tara Strong, and E.G. Daily as the Steamypuff Girls and the Prehistoric Puff Girls
 * Fifth Harmony as:
 * Ally Brooke as Bleed
 * Normani as Beanie
 * Camilla Cabello as Blitz
 * Dinah Jane as Beachball
 * Lauren Jauregui as Banshee

Teen Titans GO! Character Voices

 * Greg Cipes as Beast Boy
 * Scott Menville as Robin
 * Khary Payton as Cyborg
 * Tara Strong as Raven/Silkie
 * Hynden Walch as Starfire
 * Kevin Michael Richardson as Trigon

Additional Voices

 * Frank Welker
 * Rob Paulsen
 * Josh Keaton
 * Trevor Devall
 * Crispin Freeman
 * Wally Wingert
 * Drake Bell
 * Candi Milo
 * Lacey Chabert
 * Kari Wahlgren
 * Lloyd Sherr
 * Fred Tatasciore
 * Jason Alexander
 * Janice Kawaye
 * Seth MacFarlane
 * Carolyn Lawrence
 * Carlos Alazraqui
 * Jessica DiCicco
 * Laraine Newman
 * Tom Kenny
 * Ben Schwartz
 * Debi Derryberry
 * Audrey Wasilewski
 * Nika Futterman
 * Tara Strong
 * Edgar Wright
 * Wes Anderson
 * Nolan North
 * Jess Harnell
 * Mark Hamill
 * Rachael MacFarlane
 * Adam DeVine
 * Flula Borg
 * S. Scott Bullock
 * Fred Tatasciore
 * Tress MacNeille
 * Andy Richter
 * Jess Harnell

In the UK version, Kate Garraway and Ben Shephard replace Bob LaGrange and Nick LaNobodyKnows in the news report scene.

Mojo Jojo’s evil primates, including Rocko Socko, Ojo Tango, Hotta Watta, and Killa Drilla, appear as well, with Frank Welker, Kevin Michael Richardson, and Rob Paulsen reprising their roles from The Powerpuff Girls Movie (2002), although The Powerpuff Girls Movie 2: Generations would be a standalone sequel to The Powerpuff Girls Movie (2002).

Development
After the formation of Cartoon Network Movies, developers Nick Jennings and Bob Boyle announced a sequel to The Powerpuff Girls Movie for November 2024.

Animation
The traditional 2D animation was handled by South Korean animation studio Sunmin Image Pictures (for the 2016 Powerpuff Girls) and Rough Draft Korea (for the 1998 Powerpuff Girls) for Cartoon Network Studios in Burbank, California, while CGI animation for the 2014 Powerpuff Girls was handled at British CGI animation studio Passion Pictures, and the anime-style animation for the Powerpuff Girls Z characters was handled at Japanese animation studio Toei Animation.

Casting
On June 19, 2023, Amanda Leighton was cast as 2016 Blossom. This was followed by the casting announcements of Kristen Li, Natalie Palamides, Olivia Olson, Bill Hader, Zach Woods, Nick Kroll, Jennifer Hale, Kate Higgins, Tom Kenny, Roger L. Jackson, Cathy Cavadini, Tara Strong, and E.G. Daily the next day. On the same day, Tom Kenny confirmed that he will be voicing 2016 Professor Utonium, 1998 Professor Utonium, and the Talking Dog, replacing Tom Kane following his retirement from voice acting. Fred Tatasciore also replaces Kane as 2016 HIM and 1998 HIM.

Songs written by John Debney, Glen Ballard, Carole Bayer Sager, and Linda Thompson

 * Townsville Is Where We Belong - Amanda Leighton, Kristen Li, Natalie Palamides, Zach Woods, Nick Kroll, Bill Hader, and The Powerpuff Girls Movie 2 Cast (sung by Blossom, Bubbles, Buttercup, Brick, Boomer, Butch, and the Townsville citizens; parody of “Some Things Never Change” from Frozen II)
 * Important Things In Life - Kristen Li (parody of “When I Am Older” from Frozen II)
 * Getting The Team Together - Amanda Leighton, Kristen Li, Natalie Palamides, Cathy Cavadini, Tara Strong, and E.G. Daily (sung by the 1998-2005 Powerpuff Girls and the 2016 Powerpuff Girls; parody of “When Will My Life Begin” from Tangled)
 * A Beautiful Life - Olivia Olson (parody of “Rewrite The Stars” from The Greatest Showman)
 * What We Did In The Past - Cathy Cavadini, Tara Strong, and E.G. Daily (this is sung by the 1998-2005 and 2014 versions of the Powerpuff Girls; parody of “Waving Through A Window” from Dear Evan Hansen)
 * We Don't Want To Be Far Apart - Kristen Li and Natalie Palamides (parody of “I See The Light” from Tangled)
 * The Right Thing To Do - Amanda Leighton and Cathy Cavadini (sung by 1998 Blossom and 2016 Blossom; parody of “Show Yourself” from Frozen II)
 * Selfless - Olivia Olson (parody of “Speechless” from the 2019 remake of Aladdin)
 * The Big Finale - Amanda Leighton, Kristen Li, Natalie Palamides, Olivia Olson, Bill Hader, Zach Woods, Nick Kroll, Kate Higgins, Jennifer Hale, Tom Kenny, and Jake Goldman (a finale reprise of "Townsville Is Where We Belong" with excerpts of "What We Did In The Past", "A Beautiful Life", and "The Right Thing To Do")

End Credits Songs

 * American Girl - Bonnie McKee
 * Me & My Girls - Fifth Harmony
 * Who’s Got The Power? - Tacocat
 * The Powerpuff Girls Movie 2: Generations End Credits Music - John Debney

Bonus Songs

 * Thank You For Being A Friend - Rachel Platten
 * I'll Chase The Sky - Jessie James Decker
 * Power Up - Red Velvet
 * CAKE - Wengie
 * Deja Vu - Wengie
 * TALK TALK - Wengie, David Amber
 * TALK TALK (Japanese Version) - Wengie, eill, David Amber

Instrumental Tracks

 * Townsville Is Where We Belong (Instrumental) – John Debney, Glen Ballard, Carole Bayer Sager, Linda Thompson
 * Important Things In Life (Instrumental) – John Debney, Glen Ballard, Carole Bayer Sager, Linda Thompson
 * Getting The Team Together (Instrumental) – John Debney, Glen Ballard, Carole Bayer Sager, Linda Thompson
 * A Beautiful Life (Instrumental) – John Debney, Glen Ballard, Carole Bayer Sager, Linda Thompson
 * What We Did In The Past (Instrumental) – John Debney, Glen Ballard, Carole Bayer Sager, Linda Thompson
 * We Don't Want To Be Far Apart (Instrumental) – John Debney, Glen Ballard, Carole Bayer Sager, Linda Thompson
 * The Right Thing To Do (Instrumental) – John Debney, Glen Ballard, Carole Bayer Sager, Linda Thompson
 * Selfless (Instrumental) - John Debney, Glen Ballard, Carole Bayer Sager, Linda Thompson
 * The Big Finale (Instrumental) – John Debney, Glen Ballard, Carole Bayer Sager, Linda Thompson
 * American Girl (Instrumental) – Bonnie McKee
 * Me & My Girls (Instrumental) – Fifth Harmony
 * Who’s Got The Power? (Instrumental) – Tacocat

Score tracks by John Debney


 * 1) The City of Townsville - John Debney
 * 2) The Portal - John Debney
 * 3) Amoeba Boys - John Debney
 * 4) 1998 Girls - John Debney
 * 5) The Derbytantes' Lair - John Debney
 * 6) Maylyn / Bubbles' Recap - John Debney
 * 7) 2014 Girls - John Debney
 * 8) Blisstina - John Debney
 * 9) Time Travel - John Debney
 * 10) Mojo Jojo - John Debney
 * 11) Arrival To The 1992 Universe - John Debney
 * 12) The 1998-2005 Universe - John Debney
 * 13) The 2014 Universe - John Debney
 * 14) Tokyo City / New Townsville - John Debney
 * 15) Return To 2016 Townsville - John Debney
 * 16) Trying To Defeat Mojo Jojo - John Debney
 * 17) The Powerpuff Girls Split Up - John Debney
 * 18) A Lonely Purpose - John Debney
 * 19) Blossoms Kidnapped - John Debney
 * 20) Rescuing The Blossoms / Reconcile - John Debney
 * 21) The Powerpuff Girls of Infinite Earths - John Debney
 * 22) Final Battle - John Debney
 * 23) The Townsvilles Are Saved - John Debney
 * 24) A Promise To Keep Saving Townsville - John Debney

Remixes of Bonnie McKee's "American Girl"


 * American Girl (DJ Linuxis Remix) - Bonnie McKee
 * American Girl (Steve Aoki Remix) - Bonnie McKee
 * American Girl (Liam Walds Remix) - Bonnie McKee
 * American Girl (Oliver Remix) - Bonnie McKee
 * American Girl (Acoustic Version) - Bonnie McKee

Songs featured in the movie


 * Wonderful Life (Mi Oh My) - Matoma
 * True - Spandau Ballet
 * Life of the PRTY - PRTY H3RO
 * My Heart Will Go On (Love Theme from "Titanic") - Kenny G
 * On Top of the World - Imagine Dragons
 * I Kissed A Girl - Katy Perry
 * TALK TALK (Japanese Version) - Wengie, eill, David Amber
 * Portals (from “Avengers: Endgame”) - Alan Silvestri
 * Butter - BTS
 * Battle Royale (from “The LEGO Batman Movie”) - Lorne Balfe
 * That’s My Girl - Fifth Harmony

Songs from the trailers

 * Also Sprach Zarathustra - Richard Strauss (Teaser Trailer)
 * Let's Go - Tiësto, Icona Pop (Teaser Trailer; TV Spots)
 * Do It Like This - Daphne Willis (Official Trailer 1; International Trailer; Final Trailer; TV Spots)
 * High Hopes - Panic! At The Disco (Official Trailer 1; Official Trailer 2; Official Trailer 3; International Trailer; Final Trailer; TV Spots)
 * Shower - Becky G (Official Trailer 2; TV Spots)
 * Power - Little Mix (Official Trailer 3; TV Spots)
 * Zimzalabim - Red Velvet (Final Trailer; TV Spots)
 * Without You - David Guetta, Usher (TV Spots)
 * Starships - Nicki Minaj (TV Spots)
 * Ho Ho Ho - Sia (Christmas TV Spots)

Release
The film was theatrically released in North America and the Philippines on November 22, 2024 in 2D, 3D, IMAX, IMAX 3D, RealD 3D, Dolby Cinema, and 4DX.

A teaser trailer was released online on October 1, 2023. The film’s first official trailer was released on April 3, 2024. It was followed by a second trailer on July 1, 2024, and one month later, the third was released on August 10, 2024, until then an intranational trailer came out on August 31, 2024. The final trailer was released was released on September 27, 2024.

Marketing tie-ins
The brands that partnered with The Powerpuff Girls Movie 2: Generations include McDonald's for Happy Meal toys, Coca-Cola, Nestlé, and Kellogg's for their breakfast cereals, Unilever and Frito-Lay for all their worldwide brands, PureFoods for Tender Juicy Hotdog brands, Smart Communications, Inc., Oreo Cookies, Chips Ahoy!, Tic Tac, Xfinity, and Sky UK. LEGO sets were also made to promote the film. The Funko POP! Figures will be the same as the original ones, but with Blisstina Utonium and Jared Shapiro added.

There was also a game app based on the film alongside Warner Bros. Games, Warner Bros. Interactive Entertainment, and Cartoon Network Games.

There was also an Angry Birds Friends tournament as a promotional tie-in for the film. The tournament is called Angry Birds Friends X The Powerpuff Girls Movie 2: Generations. Players can launch the birds, destroy the cages, pop the pigs, and free the main, parallel, and alternate versions of the Powerpuff Girls.

There were also two lyric videos for “American Girl” by Bonnie McKee and “Me & My Girls” by Fifth Harmony, both are which are from The Powerpuff Girls Movie 2: Generations. Both were on all of the Warner Bros. YouTube channels worldwide. The music videos for these two songs were edited and features clips from The Powerpuff Girls Movie 2: Generations.

Home Media
The film was released on Digital HD on February 22, 2025, and on Ultra HD Blu-ray, Blu-ray and DVD on March 4, 2025 by Warner Bros. Home Entertainment. It includes deleted scenes, the filmmakers commentary, the "Behind-The-Puffs" featurette, the outtakes, the nine digital shorts from Seasons 1 and 2 of the 2016 reboot (Air Buttercup, Bubbles' Beauty Blog... but on Video, Run Blossom Run, Ping Pong Z, Bubbs & Donny Get the Mail, Bedtime, Mojo Builds a Shelf, I’ll Be Bake, and Blissfully Unaware), a sing-along version, and a teaser trailer for 2025's Storks 2. It was also included in the Powerpuff Girls Complete Series DVD along with The LEGO Movie 3: A Powerpuff Adventure. The film was debuted on Netflix on March 8, 2025 and on Apple TV+ on March 15, 2025. The film headed to Amazon Prime Video and HBO Max on April 24, 2025, and on Hulu on May 3, 2025, joining The LEGO Movie 3: A Powerpuff Adventure. It also released on WarnerUniversal All Access on May 28, 2025, the same day the streaming service launched.

Television premiere
The film made its television premiere on Cartoon Network on September 26, 2025. It also had its premiere on Cartoon Network on the same day in Southeast Asia, and was simulcast on Boomerang, Oh!K, WarnerTV, HBO, HBO Family, Cartoonito, Toonami, Adult Swim, Universal TV, Universal Kids, Diva, Studio Universal, TNT, TBS, Syfy, TruTV, NBC, E!, and DreamWorks Channel.

Box Office
The Powerpuff Girls Movie 2: Generations grossed $434 million in the United States and Canada, and $639.4 million in other territories, for a worldwide total of $1.073 billion. The film had a worldwide opening of $244.5 million, the 46th highest ever, and 3rd biggest for an animated film. It crossed the billion dollar mark on February 4, 2025, becoming the 43rd film as well as the second Warner Animation Group film to ever do so. It was also the second film released by the Warner Animation Group to cross the milestone.

United States and Canada
The Powerpuff Girls Movie 2: Generations set the records on Fandango for most tickets sold by an animated film in that frame (besting Despicable Me 3). The film was projected to gross $30–35 million in its opening weekend, with some predicting it could debut as high as $200 million. It played in 4,575 theaters, the second-most all-time behind The LEGO Movie 3: A Powerpuff Adventure. The Powerpuff Girls Movie 2: Generations made $47.4 million on its first day, beating projections, including $12 million from Thursday night previews, the second-highest amount for an animated film, behind Teen Titans Go! To the Movies. The film went on to debut to $120.9 million over the weekend, finishing first at the box office. Executives at Warner Bros. were satisfied with the debut, since it continued the Warner Animation Group's "remarkable consistency" at the box office and showed "proof of audiences' long-time love for the Powerpuff Girls franchise." Additionally, it was the best opening of the series, the biggest for a PG-rated film and the fourth-highest of all-time for an animated film. In its second weekend, The Powerpuff Girls Movie 2: Generations made $59.7 million and retained the top spot at the box office. It grossed $33.9 million in its third weekend. The film outgrossed its predecessor to become the highest-grossing film of all time domestically.

Other territories
The film opened day-in-date with the U.S. in 37 countries (64% of its total market), and was projected to gross around $100 million abroad for a global debut of $260 million. In China, it was expected to debut to $15–20 million. The film's largest markets were Japan ($90.1 million), the United Kingdom ($79.9 million, third highest all-time for an animated film), Mexico ($72 million), Brazil ($32.5 million), France ($29.2 million), China ($29.1 million), Argentina ($28.9 million), Australia ($28.9 million), and South Korea ($24.7 million).

Critical response
On review aggregation website Rotten Tomatoes, the film holds an approval rating of 100% based on 421 reviews, with an average rating of 10/10. The website's critics consensus reads, "Heartwarming, funny, and beautifully animated, The Powerpuff Girls Movie 2: Generations brings the family together." Metacritic, which uses a weighted average, assigned the film a score of 84 out of 100 based on 57 critics, indicating "universal acclaim." Audiences polled by CinemaScore gave the film an average grade of "A+" on an A+ to F scale, while those at PostTrak gave it an overall positive score of 100% and a 100% "definite recommend."

The film received a four-star rating from Matt Zoller Seitz of RogerEbert.com, who wrote, "This film is even better than the last two 2021 Warner Animation Group films we had: Tom & Jerry and Space Jam: A New Legacy." The Washington Post's Ann Hornaday also gave the film 5 out of 5 stars and praised its, "visually dazzling concoction of wily schemes and daring adventures", as well as achieving, "a continuation of Cartoon Network's theatrical reputation." Peter DeBruge of Variety wrote, "The Powerpuff Girls Movie ushered in the era of traditionally animated cartoon features, and this sequel wraps up the saga beautifully. At least, for now." The Daily Telegraph 's Robbie Collin wrote, "The Powerpuff Girls Movie 2 reaffirms that the Warner Animation Group, at their best, are like no other animation studio around."

Trivia

 * Warner Animation Group was not involved with the first Powerpuff Girls Movie.
 * The first time the 2016 reboot got a feature film.
 * It is revealed that the 1998 Powerpuff Girls and 2016 Powerpuff Girls are from separate universes.
 * Nick Jennings and Bob Boyle replace Craig McCracken from the first film, though McCracken serves as one of the executive producers of the film.
 * John Debney replaces James L. Venable from the first film.
 * Brick is voiced by Bill Hader, who also voiced Wade Wilson / Deadpool in The LEGO Movie 3: A Powerpuff Adventure, Fear in Inside Out, Leonard Mudbeard in The Angry Birds Movie, Firewater, El Guaco and Tequila in Sausage Party, and Flint Lockwood in Cloudy with a Chance of Meatballs.
 * Boomer is voiced by Zach Woods, who also voiced Zane in The LEGO Ninjago Movie and The LEGO Movie 3: A Powerpuff Adventure.
 * Butch is voiced by Nick Kroll, who also voiced Shazam in The LEGO Movie 3: A Powerpuff Adventure, Sergei in The Secret Life of Pets 2, Uncle Fester in The Addams Family, Gunter in Sing, Professor Poopypants in Captain Underpants: The First Epic Movie, and Douche in Sausage Party.
 * The feature debut of the Rowdyruff Boys.
 * The film serves as the series finale of the 2016 reboot.
 * The narrator never says "The City of Townsville" at the beginning of the movie, but Bubbles reads these words on the papers before the curtains even open.
 * The film takes place after the events of Sideline Dad.
 * The Teen Titans recall the events of TTG v PPG.
 * The scene where 2016 Blossom and Bliss sang "That's My Girl" by Fifth Harmony while fighting off Mojo Jojo's evil primates is similar to the scene where Katie Mitchell and Rick Mitchell sang "Live Your Life" by Rihanna and T.I. while fighting off the PAL Max Prime robots from the 2021 Netflix and Sony Pictures Animation film The Mitchells vs. the Machines.
 * The Powerpuff Time Machine is the third character for Olivia Colman to voice in animated film, after PAL from The Mitchells vs. the Machines (2021) and Donka from Ron's Gone Wrong (2021).
 * Violet is Abbi Jacobson's third animated character after Nya from The LEGO Ninjago Movie (2017) and Katie Mitchell from The Mitchells vs. the Machines (2021).
 * Bunny is Awkwafina's sixth animated character after the Quail from Storks (2016), Courtney from The Angry Birds Movie 2 (2019), Otto from The SpongeBob Movie: Sponge on the Run (2020), Sisu from Raya and the Last Dragon (2021), and Ms. Tarantula from The Bad Guys (2022).
 * Bloom is Rachel Bloom's fourth animated character after Silver from The Angry Birds Movie 2 (2019), Queen Barb from Trolls World Tour (2020), and Op from Extinct (2021).
 * This is also the first time The Powerpuff Girls (2016) is PAL pitched in some countries, as when the series aired, the pitch remained the same.
 * Both the 2019 Warner Bros. logo and the 2021 Warner Animation Group logo appeared as easter eggs in this film:
 * They appeared on a chart that 2016 Blossom showed the Girls' past selves in the "Getting The Team Together" song sequence.
 * They appeared again as constellations throughout the "A Beautiful Life" song sequence.
 * They appeared again on two of the mirrors when the two Blossoms were singing the last lyrics of "The Right Thing To Do".
 * An image of Ultrakatty from The LEGO Movie 2: The Second Part is seen on one of the lockers.
 * Migo, Meechee, Gwangi, Fleem, and Kolka from Smallfoot can be seen as plush toys in the Powerpuff Girls’ room.
 * Diamond Destiny from Storks is seen on a baby carriage when Bubbles sings "Important Things In Life".
 * Wolf Pack leaders Alpha and Beta from Storks appear as bobbleheads on one of the vehicles.
 * Krypto from DC League of Super Pets makes a cameo on a sidewalk.
 * A Townsville citizen wears the same robe as the Stonekeeper.
 * Harley Quinn's mallet from The LEGO Batman Movie is seen inside one of the lockers.
 * The Ultimate Ultimate Weapon from The LEGO Ninjago Movie made a cameo appearance in the Girls' closet.
 * A poster for The LEGO Movie 2: The Second Part is seen at the back of the bus.
 * Blue Falcon (Brian) and Dynomutt appear as two figurines among Bubbles’ 3D printed models of the Space Tow Truck characters.
 * Pigeon Toady appears a figurine in the Powerpuff Girls’ room.
 * LeBron James from Space Jam: A New Legacy makes a cameo appearance as a bobblehead in the school bus.
 * Butch from Tom & Jerry can be seen in a "Hang In There, Baby" poster.
 * Emmet, Wyldstyle, Unikitty, Benny, MetalBeard, Batman, and Vitruvius from The LEGO Movie can be seen as regular LEGO figures among Bubbles’ 3D printed models of the Space Tow Truck characters.
 * The Cat in the Hat and his two things (Thing One and Thing Two) make a cameo appearance in one scene during the “Townsville Is Where We Belong” song sequence. This could tease the upcoming animated Cat in the Hat film, and the spin-off Thing One and Thing Two, as part of Warner Animation Group’s partnership with Dr. Seuss Enterprises.
 * Wile E. Coyote and the Road Runner from Coyote vs. Acme make a cameo appearance in another scene during the “Townsville Is Where We Belong” song sequence.
 * Funko versions of the Powerpuff Girls appear beside Bubbles’ computer on the table.
 * The books The Ice Dragon, Oh, the Places You’ll Go!, and Toto: The Dog-Gone Amazing Story of The Wizard of Oz appear in a bookshelf.
 * Bugs Bunny and Daffy Duck appear as small figurines in Bubbles’ locker.
 * Rex Dangervest from The LEGO Movie 2: The Second Part makes a cameo as a keychain on Professor Utonium’s car keys.
 * The Mystery Machine from Scoob! makes a cameo appearance parked near the Derbytantes’ lair.
 * Alongside the Funko versions, LEGO versions of the Powerpuff Girls are seen on the table.
 * Pete from Space Jam: A New Legacy makes a cameo appearance as a hanging accessory on the mirror on one of the vehicles.
 * Twilight Sparkle, Pinkie Pie, Fluttershy, Rainbow Dash, Applejack, and Rarity from the untitled My Little Pony: The Movie sequel appear as figurines on a small table in the Powerpuff Girls’ room.
 * Red, Chuck, and Bomb from The Angry Birds Movie 3 appear as plush toys in the Powerpuff Girls’ room.
 * A poster of The LEGO Movie can be seen in the 2014 Powerpuff Girls' house.
 * A scene from The LEGO Batman Movie can be shown on the screen of the Townsville Multiplex during the final battle scene.

Follow-up television spin-off
It's Blossom! is an HBO Max and WarnerUniversal All Access original animated series produced by Warner Bros. Television Studios, Warner Animation Group, Cartoon Network Studios, and Sunmin Image Pictures.

Taking place after the events of The Powerpuff Girls Movie 2: Generations, Blossom Powerpuff stars in her own show, with new songs, new friends, new life, and new fun video chats to have with real people and kids, and even teens!

Alongside The LEGO Series, the series premiered on HBO Max and WarnerUniversal All Access on May 28, 2025.

Transcript
Main article: The Powerpuff Girls Movie 2: Generations/Transcript